Evidence map›Paper›PMID 41191275›Full record

ArticleAnnals of biomedical engineering2026

Superior Biomechanics of Patient-Specific Mandibular Reconstruction Plate: A Validated Computational-Experimental Framework.

Shengping Zhong, Yi Zhang, Qimin Shi, Jeroen Van Dessel, Joris Geusens, Sam Coppieters, Bart Van Meerbeek, Constantinus Politis, Shoufeng Yang, Yi Sun

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Article in Annals of biomedical engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shengping ZhongDepartment of Imaging & Pathology, Biomedical Sciences Group, KU Leuven, Kapucijnenvoer 7, Box 7003, 3000, Leuven, Belgium.
Yi ZhangElooi Laboratory, Department of Materials Engineering, KU Leuven, Gent Campus, Gebroeders de Smetstraat 1, 9000, Gent, Belgium.
Qimin ShiDepartment of Imaging & Pathology, Biomedical Sciences Group, KU Leuven, Kapucijnenvoer 7, Box 7003, 3000, Leuven, Belgium.
Jeroen Van DesselDepartment of Imaging & Pathology, Biomedical Sciences Group, KU Leuven, Kapucijnenvoer 7, Box 7003, 3000, Leuven, Belgium.
Joris GeusensOral and Maxillofacial Surgery, University Hospitals Leuven, Kapucijnenvoer 33, 3000, Leuven, Belgium.
Sam CoppietersElooi Laboratory, Department of Materials Engineering, KU Leuven, Gent Campus, Gebroeders de Smetstraat 1, 9000, Gent, Belgium.
Bart Van MeerbeekDepartment of Oral Health Sciences, Biomaterials Research Group, KU Leuven & Dentistry, University Hospitals Leuven, Kapucijnenvoer 7, Box 7001, 3000, Leuven, Belgium.
Constantinus PolitisDepartment of Imaging & Pathology, Biomedical Sciences Group, KU Leuven, Kapucijnenvoer 7, Box 7003, 3000, Leuven, Belgium.
Shoufeng YangChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, No. 266 Fangzheng Avenue, Chongqing, 400714, P.R. China.
Yi SunOral and Maxillofacial Surgery, University Hospitals Leuven, Kapucijnenvoer 33, 3000, Leuven, Belgium. yi.sun@uzleuven.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient-specific mandibular reconstruction plates (PSMRPs) have gained prominence for their precise adaptation to mandibular contours and reported enhanced mechanical performance compared to the manual-bent mandibular reconstruction plates (MBMRPs). However, clinical adoption remains cautious due to insufficient biomechanical evidence directly and carefully comparing their performance. Hence, this study investigated the biomechanical behavior between two mandibular reconstruction assemblies with MBMRP and PSMRP, respectively. Mechanical properties of these two reconstruction systems, including yield and ultimate strength, fatigue strength and life, were evaluated through finite element analyses (FEA) and biomechanical tests, during which digital image correlation (DIC) was used to measure full-field displacements and strains. Results revealed that the PSMRP provides higher stiffness and longer fatigue life to the reconstruction system than the MBMRP, signified by above 33% higher stiffness in the quasi-static compression and exceeding 90% more life cycles in the cyclic test, respectively. These findings not only highlight the biomechanical advantages of PSMRP over MBMRP but also underline the strong correlation between FEA predictions and experimental outcomes in the mandibular reconstruction system, validating the FEA's utility for preoperative biomechanical evaluation. Collectively, this work provides critical evidence supporting the biomechanical superiority of PSMRPs in mandibular reconstruction-potentially reducing risks of plate failure and reoperation-and establishes a translational framework that combines computational and experimental biomechanics to advance patient-specific implant design in oral, dental, and craniofacial surgery.

Indexed as

Bone PlatesMandibleMandibular ReconstructionBiomechanical PhenomenaFinite Element AnalysisHumansAdditive manufacturingBiomechanical behaviorDigital image correlationFinite element analysisMandibular reconstructionPatient-specific implant

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.