Evidence map›Paper›PMID 41191226›Full record

ArticleOral radiology2026

Imaging diagnosis of mucoepidermoid carcinoma with intratumoral bone formation: a case report.

Noriko Yamao, Hiroaki Shimamoto, Maziahtul Zawani Munshi, Danielle Ayumi Nishimura, Naoko Takagawa, Varisa Assapattarapun, Katsutoshi Hirose, Kaori Oya, Toshihiro Uchihashi, Sven Kreiborg and 2 more

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In one paragraph

Article in Oral radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Noriko YamaoDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Hiroaki ShimamotoDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan. shimamoto.hiroaki.dent@osaka-u.ac.jp.ORCID http://orcid.org/0000-0001-5609-266X
Maziahtul Zawani MunshiDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Danielle Ayumi NishimuraDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Naoko TakagawaDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Varisa AssapattarapunDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Katsutoshi HiroseDepartment of Oral and Maxillofacial Pathology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Kaori OyaClinical laboratory, The University of Osaka Dental Hospital, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Toshihiro UchihashiDepartment of Oral and Maxillofacial Surgery, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Sven KreiborgDepartment of Pediatric Dentistry and Clinical Genetics, School of Dentistry, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, Copenhagen, DK-2200, Denmark.
Sanjay M MallyaSection of Oral and Maxillofacial Radiology, UCLA School of Dentistry, 10833 Le Conte Ave, Los Angeles, CA, 90095-1668, USA.
Fan-Pei Gloria YangDepartment of Oral and Maxillofacial Radiology, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, 565-0871, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucoepidermoid carcinoma (MEC) is the most frequent salivary gland malignancy. Rarely, intra tumor bone formation may occur. To date there have been only two reports of MEC with bone formation in the oral and maxillofacial region. We report a case of MEC in the sublingual gland with intratumor bone formation involving a 78-year-old woman. The study presents the imaging findings of the lesion across multiple modalities. Multi-detector row computed tomography (MDCT) imaging revealed a 21 × 18 × 12 mm mass in the left side of floor of the mouth, containing multiple calcified-like high CT numbers (≥ 400 HU). Magnetic resonance imaging (MRI) revealed a 28 × 21 × 11 mm mass that was isointense to muscle on T1-weighted images, intermediate signal intensity on short tau inversion recovery (STIR) images and with heterogeneous contrast enhancement. In addition, multiple signal voids suspicious for calcification were observed inside the lesion. Ultrasonography showed a well-defined hypoechoic lesion within the left sublingual gland and multiple hyperreflective bodies with acoustic shadows inside the lesion. Histopathologically, the lesion was diagnosed as intermediate-grade MEC with bone formation inside the lesion. The identification of calcifications on the MDCT examination was a key prompt to further investigate the nature of the lesion.

Indexed as

Carcinoma, MucoepidermoidSublingual Gland NeoplasmsAgedDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingBone formationCalcificationImaging diagnosisMDCTMucoepidermoid carcinoma

Identifiers

PMID41191226

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.