ArticleMycopathologia2025
Sporothrix brasiliensis Atypical Dimorphism in Tissue.
Article in Mycopathologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Sporotrichosis, caused by the thermodimorphic fungus Sporothrix brasiliensis, is an emerging zoonotic infection in Brazil and other Latin American countries. Typically, the parasitic form in host tissue is yeast; however, we report three cases in immunocompromised patients exhibiting simultaneous yeast and mycelial structures in biopsies. Identification of S. brasiliensis was confirmed through calmodulin gene sequencing, with phylogenetic analysis supporting species-level classification. Direct examination and histopathology revealed both budding yeast cells (3-8 μm) and hyphae, a rare morphological phenomenon previously unreported for this species in humans. This atypical dimorphism may be influenced by local tissue conditions, such as oxygen exposure and lower temperatures, and has significant diagnostic implications. Recognition of polymorphic forms is essential for pathologists and mycologists, highlighting the evolving histopathological and diagnostic challenges in sporotrichosis.
Indexed as
Identifiers
41191178What OpenQuestion holds
Registered trials
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