ReviewCurrent neurology and neuroscience reports2025
Neurogenetic Disorders with Hearing Loss: Mechanisms, Classifications, and Emerging Insights.
Review in Current neurology and neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Clinical and genetic heterogeneity of syndromic hearing loss and its non-syndromic hearing loss mimics.Molecular medicine (Cambridge, Mass.) · 2026Article
- Neurodevelopmental Disorder with Psychomotor Delay, Hearing Loss, and Spasticity Caused by Compound HeterozygousJournal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewNeurogenetic disorders associated with hearing loss represent a rapidly expanding field, with recent gene discoveries revealing convergent mechanistic themes affecting both the nervous and auditory systems. Collectively, these findings highlight shared vulnerabilities of neural and auditory tissues. We summarize gene discoveries from 2021 to 2025, moving beyond classic syndromes to highlight newly implicated genes within mechanistic categories and discuss their implications for diagnosis, counseling, and therapeutic development. RECENT
findingsWe describe 38 genes with combined neurodevelopmental and auditory phenotypes, providing an updated view of the field. We explore common developmental pathways and, when possible, propose explanations for the variable expression of hearing impairment observed across disorders. A deeper understanding of the mechanisms linking the nervous and auditory systems is essential for clarifying the pathogenesis of auditory syndromes. The emerging picture underscores that hearing loss can serve as an early marker of systemic neurogenetic disease that may offer a window of opportunity for timely intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.