Evidence map›Paper›PMID 41191066›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Microcystic macular edema in eyes with idiopathic epiretinal gliosis: A retrospective analysis before and after vitreomacular surgery : Short title: microcystic macular edema in idiopathic epiretinal gliosis.

Denise Vogt, Julia Zimmermann, Adnan Kilani, Melih Parlak, Ricarda G Schumann, Armin Wolf, Efstathios Vounotrypidis

Abstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Denise VogtDepartment of Ophthalmology, University Hospital of Ulm, Ulm, Germany. denise.vogt@uniklinik-ulm.de.ORCID http://orcid.org/0000-0002-1032-6675
Julia ZimmermannDepartment of Ophthalmology, University Hospital of Ulm, Ulm, Germany.
Adnan KilaniDepartment of Ophthalmology, University Hospital of Ulm, Ulm, Germany.
Melih ParlakDepartment of Ophthalmology, University Hospital of Ulm, Ulm, Germany.
Ricarda G SchumannDepartment of Ophthalmology, University Hospital of Ulm, Ulm, Germany.
Armin Wolf *Department of Ophthalmology, University Hospital of Ulm, Ulm, Germany.
Efstathios Vounotrypidis *Department of Ophthalmology, University Hospital of Ulm, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate incidence and clinical course of microcystic macular edema (MME) in eyes with idiopathic epiretinal membranes (iERM) before and after surgery.

methodsOf 1283 eyes that underwent vitrectomy with membrane peeling, 170 eyes were retrospectively analysed. All eyes had iERM and at least one postoperative control with retinal imaging. MME and cystoid macular edema (CME) were assessed by optical coherence tomography (OCT), along with demographic and clinical data. Correlations with functional outcomes were statistically significant at p < 0.05.

resultsAt baseline, 42 eyes (25%) had MME, 18 eyes (11%) had combined MME + CME and 110 eyes (64%) had no edema. The mean postoperative follow-up was 7.1 ± 5.9 months. All three groups showed significant improvement in visual acuity (VA), greatest in the no-edema group (p < 0.001). Incidence of MME increased with ERM severity (p = 0.033). At three months postoperatively, MME persisted in 32/159 eyes, resolved in 25, newly developed in 20, and was absent in 82/159 eyes, with a significant difference in VA between groups (p < 0.001). After 12 months, persistent MME reduced to 4/26 eyes, resolution of MME was seen in 6, new MME in 5 and 11/26 eyes still had no edema, with no significant VA between the groups (p = 0.206).

conclusionOur study demonstrates that visual recovery occurred irrespective of MME status. In advanced iERM stages, MME was more frequently observed and associated with delayed visual improvement, particularly when it developed or persisted after surgery. Despite its early effects, MME does not seem to significantly affect long-term visual outcomes.

Indexed as

Epiretinal MembraneGliosisMacula LuteaMacular EdemaVisual AcuityVitrectomyAgedAged, 80 and overFemaleFluorescein AngiographyFollow-Up StudiesHumansIncidenceMaleMiddle AgedPostoperative PeriodCystoid macular edemaIdiopathic epiretinal membraneMicrocystic macular edema membrane peelingOptical coherence tomographyVitrectomyVitreomacular interface vitreomaculopathy

Identifiers

PMID41191066
PMCPMC12923396

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.