Evidence map›Paper›PMID 41191059›Full record

ArticleArchives of microbiology2025

Whole genome sequencing to assess the safety and probiotic potential of Pediococcus pentosaceus L1 isolated from pickled radish.

Ghulam Mustafa, Chen Liu, Dongmei Wang, Jijiang Dong, Jinping Zhou, Laifeng Chen, Yini Ma, Zhenhui Cao, Le Xu, Qiuye Lin

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The therapeutic potential ofFrontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ghulam Mustafa *College of Food Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Chen Liu *Faculty of Animal Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Dongmei WangCollege of Food Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Jijiang DongCollege of Food Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Jinping ZhouCollege of Food Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Laifeng ChenCollege of Food Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Yini MaCollege of Food Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Zhenhui CaoFaculty of Animal Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China.
Le XuFaculty of Animal Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China. 2023037@ynau.edu.cn.
Qiuye LinCollege of Food Science and Technology, Yunnan Agricultural University, Heilongtan, North Suburb, Kunming, 650201, China. linqiuye@ymu.edu.cn.

Funding

Young Top-notch Talent of Yunnan Xingdian Support Project for High Level Talents YNWR-QNBJ-2018-137Yunnan Provincial International Science and Technology Commissioner (individual) Grant No. 202403AK140032
6 · The paper itself

Abstract

This research aimed for the safety and probiotic potential assessment of Pediococcus pentosaceus L1, isolated from pickled radish, through its whole genome sequencing analysis and in vitro evaluation. The genome size of Ped. pentosaceus L1 was 1,751,467 bp long with an average guanine-cytosine (GC) ratio of 37.41% and contained 1739 genes in the coding region. The functional annotation of the L1 strain demonstrated that it exhibited excellent probiotic potential and health-promoting properties, with numerous genes linked to the carbohydrate metabolism system, stress resistance, and environmental adaptation. The analysis of virulence factor and antimicrobial resistance indicated the absence of any virulence-related or antibiotic resistance genes in Ped. pentosaceus L1, adding value to its safety profile. In vitro experiments showed that Ped. pentosaceus L1 presented high cell surface hydrophobicity, strong antioxidant activity, no hemolytic activity, and did not synthesize biogenic amines including cadaverine, putrescine, or agmatine. Additionally, its auto- and co-aggregation survival rates indicated its probiotic potential. Ped. pentosaceus L1 also exhibited exceptional exopolysaccharide (EPS) production potential, achieving an enhanced EPS yield in a glucose-supplemented medium. Together, all these characteristics make Ped. pentosaceus L1 an optimistically safe choice for use as a potential probiotic.

Indexed as

Genome, BacterialPediococcus pentosaceusProbioticsRaphanusAntioxidantsFood MicrobiologyPolysaccharides, BacterialVirulence FactorsWhole Genome SequencingAntioxidantsPolysaccharides, BacterialVirulence FactorsExopolysaccharidesGenome analysisPediococcus pentosaceusProbiotic characteristicsSafety

Identifiers

PMID41191059

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.