ArticleJournal of feline medicine and surgery2026
Detection of intracellular bacteria in feline inflammatory cardiac, hepatic and renal diseases: a retrospective study using fluorescent in situ hybridisation.
Article in Journal of feline medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectivesThe aims of the present study were to determine whether bacteria are present in feline cardiac, hepatic and renal tissues where inflammation has been identified and to compare the location of any bacteria with areas of inflammation within those tissues. Fluorescent in situ hybridisation (FISH) facilitates visualisation of intracellular bacteria in tissues. There is little research looking at the role of intracellular bacteria in inflammatory disease within feline medicine.MethodsStudy group (SG) cases were selected from Ross University School of Veterinary Medicine's pathology archive for 2012-2022. A total of 23 cases fulfilled the inclusion criteria. Three sequential sections were assessed with FISH (using eubacterial and non-eubacterial probes) and haematoxylin and eosin staining. Control group (CG) cases were selected from the same archive (n = 6) where death was trauma related; no other disease states were noted and the same three tissues were available for testing. Known bacteria-positive sections were included with each batch of slides processed to confirm successful hybridisation.ResultsOf the SG cases, 52.2% (95% confidence interval [CI] 30.6-73.2) demonstrated bacteria within some or all tissues tested, and 78.3% (95% CI 56.3-92.5) demonstrated the presence of inflammatory cells (ICs) in one or more tissues. Of the IC-positive SG cases, 61.1% (95% CI 35.7-82.7) demonstrated bacteria using FISH; the presence of bacteria in either the liver or kidney was frequently associated with the presence of ICs in 77.7% (95% CI 40.0-97.2) and 80% (95% CI 28.4-99.5) of cases, respectively. Among these, IC distribution did not match bacterial distribution. Of the CG cases, 83.3% (95% CI 35.9-99.6) were negative for ICs. Notably, in the IC-negative CG cases, two (40%) were positive for bacteria using FISH (95% CI 5.3-85.3). The Pearson χ
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.