Evidence map›Paper›PMID 41190606›Full record

ReviewAnnals of medicine2025

Advancing post-stroke blood pressure management: an individualized BP strategy for function optimization.

Suli Yu, Chi Liu

Abstract readReview
In one paragraph

Review in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Suli YuLimb Function Reconstruction Center, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.
Chi LiuDepartment of Geriatrics Center & National Clinical Research Center for Aging and Medicine, Jing'an District Centre Hospital of Shanghai, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke remains a major global public health concern and a leading cause of death, disability, and dementia. Despite being the most important and modifiable risk factor for stroke, Blood pressure (BP) management remain controversial and challenging in post-stroke population.

objectiveThis study explores the critical role of blood pressure in supporting post-stroke neural function and discusses the need for individualized BP targets to optimize brain reorganization and functional rehabilitation.

methodsFor this narrative review, PubMed, EMBASE (from inception o Jan 1,2024) have been searched about studies that investigated the relationship between blood pressure control and post-stroke function outcomes. A total of 21 articles were included, and we identified a critical gap in the current literature on BP management following stroke: While current clinical guidelines provide stratified recommendations based on stroke acuity, type, and treatment modality, they often overlook functional recovery as a core therapeutic objective.

resultsEmerging evidence suggests that optimal BP targets for post-stroke recovery are not universal but are evidence indicates that optimal BP levels vary across stroke subtypes and hemodynamic profiles. Existing strategies prioritize mortality reduction and recurrence prevention rather than functional restoration, overlooking outcomes vital to survivors' independence.To address this gap, we propose a conceptual framework that aligns BP regulation with functional outcomes and utilizes artificial intelligence (AI) and data-driven technologies to tailor BP control strategies to each patient's unique physiological and neurological profile.

conclusionThis individualized and function-oriented BP management represents a paradigm shift in post-stroke care. This personalized approach holds promise for improving rehabilitation outcomes and advancing the integration of precision medicine in stroke care.

Indexed as

Antihypertensive AgentsBlood PressureHypertensionStrokeStroke RehabilitationHumansPrecision MedicineRecovery of FunctionRisk FactorsAntihypertensive Agentsblood pressurebrain reorganizationdeep reinforcement learningfunction prognosisStroke

Identifiers

PMID41190606
PMCPMC12590565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.