ArticleClinical physiology and functional imaging2025
Echocardiographic assessment of peak atrial longitudinal strain in paroxysmal atrial fibrillation patients compared to age-matched controls.
Article in Clinical physiology and functional imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Echocardiographic assessment of peak atrial longitudinal strain in paroxysmal atrial fibrillation patients compared to age-matched controls.Clinical physiology and functional imaging · 2025Article
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6 authors.
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Abstract
aimTo investigate left atrial (LA) function assessed by peak atrial longitudinal strain (PALS) in an elderly population with silent paroxysmal atrial fibrillation (PAF) compared to age-matched control group.
methodsFrom the STROKESTOP2-study, patients with newly diagnosed silent PAF were enrolled together in a randomly selected age-matched control group. All patients had NT-proBNP levels between 125 and 900 ng/L. Echocardiographic examinations were performed and analyzed offline using dedicated software. In addition to conventional echocardiographic variables, PALS was measured using a two-dimensional speckle tracking (2D-ST) biplane.
resultsThe study population (mean age 76 ± 0.3) demonstrated significantly reduced PALS in patients with PAF (N = 69) compared to controls (N = 94) (23.9% ± 6.5% vs 30.7% ± 7.6%, p < 0.001). In the PAF group, 29 (42%) patients had normal LA volume index (LAVI) defined as
conclusionPALS was significantly reduced in PAF patients even in the absence of significant LA remodeling. PALS <22% predicts risk for silent PAF in general elderly population. In high-risk patients PALS could be used for AF screening enrichment.
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