ReviewAnnals of African medicine2026
Emergence and Spread of Carbapenem Antimicrobial Resistance: A Review on Mechanism of Drug Resistance and Laboratory Detection.
Review in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
abstractAntimicrobial resistance (AMR) is a growing global concern, exacerbated by the misuse of antimicrobial agents in humans and animals. Carbapenems, a category of β-lactam antibiotics, play a vital role in the management of severe infections induced by resistant bacterial strains. However, the rise of carbapenem-resistant Enterobacteriaceae (CRE) has emerged due to overuse and the development of carbapenemases, enzymes that hydrolyze carbapenems. CRE infections are associated with high mortality rates and limited treatment options, necessitating combination therapy approaches. Effective detection methods for carbapenemase production include phenotypic tests like the Modified Hodge Test and Carba NP test, alongside molecular methods. Overall, a multifaceted approach is essential to combat the threat posed by CRE and Carbapenemase-producing Enterobacterales, ensuring effective management and treatment of resistant infections.
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