Evidence map›Paper›PMID 41190186›Full record

ReviewChemical science2025

Carbene-catalytic enantioselective synthesis of chiral macrocycles.

Huikun Yan, Yuanyuan Zhu, Gongming Yang, Shuangxi Gu

Abstract readReview
In one paragraph

Review in Chemical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huikun YanState Key Laboratory of Green and Efficient Development of Phosphorus Resources, Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering & Pharmacy, Wuhan Institute of Technology Wuhan 430205 China ygm18@tsinghua.org.cn shuangxigu@163.com.
Yuanyuan ZhuSchool of Chemistry and Environmental Engineering, Wuhan Institute of Technology Wuhan 430205 China.
Gongming YangState Key Laboratory of Green and Efficient Development of Phosphorus Resources, Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering & Pharmacy, Wuhan Institute of Technology Wuhan 430205 China ygm18@tsinghua.org.cn shuangxigu@163.com.ORCID https://orcid.org/0000-0002-5480-7833
Shuangxi GuState Key Laboratory of Green and Efficient Development of Phosphorus Resources, Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering & Pharmacy, Wuhan Institute of Technology Wuhan 430205 China ygm18@tsinghua.org.cn shuangxigu@163.com.ORCID https://orcid.org/0000-0003-0159-4616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chiral macrocyclic units are not only prevalent in natural products, bioactive molecules, and functional compounds, but also play significant roles in synthetic and host-guest chemistry. Although extensive efforts have been devoted to constructing chiral macrocycles, few methods have been disclosed to date. Consequently, the rapid enantioselective construction of optically active macrocycles remains a formidable challenge.

Identifiers

PMID41190186
PMCPMC12581185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.