Evidence map›Paper›PMID 41189997›Full record

ArticleFrontiers in cardiovascular medicine2025

The kinetics of CA125 levels as a prognostic marker for in-hospital mortality in patients with acute heart failure: a pilot study.

Hai Nguyen Ngoc Dang, Thang Viet Luong, Thang Chi Doan, Duy Khanh Tran, Tien Hoang Anh, Duong Hung Tran, Hung Minh Nguyen, Dung The Bui, Hoa Tran

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Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Hai Nguyen Ngoc Dang *Faculty of Medicine, Duy Tan University, Da Nang, Vietnam.
Thang Viet Luong *University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Thang Chi Doan *Cardiovascular Center, Hue Central Hospital, Hue, Vietnam.
Duy Khanh TranFaculty of Medicine, Duy Tan University, Da Nang, Vietnam.
Tien Hoang AnhUniversity of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Duong Hung TranUniversity of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Hung Minh NguyenVietnam National Heart Institute, Bach Mai Hospital, Ha Noi, Vietnam.
Dung The BuiCardilogy Department, University Medical Center, Ho Chi Minh, Vietnam.
Hoa TranCardilogy Department, University Medical Center, Ho Chi Minh, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute heart failure (AHF) carries a high risk of in-hospital mortality, and identifying reliable prognostic biomarkers remains challenging. Cancer antigen 125 (CA125) has recently emerged as a potential marker in heart failure, but its prognostic value for in-hospital mortality in AHF is unclear. This pilot study examined the kinetics of CA125 and its association with in-hospital mortality in AHF patients. Methods: In this single-center prospective cohort study, 80 participants were enrolled and divided into three groups: AHF ( Results: CA125 levels were significantly higher in the AHF group (median 127.5 U/ml) compared to the CHF (15.8 U/ml, Conclusion: CA125 levels are higher in AHF patients than in CHF patients and controls. An increase in CA125 after 7 days of treatment compared with admission levels is linked to higher in-hospital mortality. Larger multicenter studies are needed to confirm the role of CA125 in heart failure management.

Indexed as

acute heart failurebiomarkercancer antigen 125in-hospital mortalityprognosis

Identifiers

PMID41189997
PMCPMC12580267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.