ArticleHealth science reports2025
Major Elective Surgery Impact on Performance Status in Older Adults: A Prospective Observational Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Perioperative care in older adults: a narrative review.European geriatric medicine · 2026Review
- Major Elective Surgery Impact on Performance Status in Older Adults: A Prospective Observational Study.Health science reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: This study evaluated the impact of major elective surgery on performance status, defined as functional and cognitive status, in older adults 3 months postoperatively. Secondary endpoints included assessing the need for domiciliary care, rehospitalization, or institutionalization, and evaluating associations with anesthesia type. Methods: In this observational prospective cohort study, 169 patients aged ≥ 70 underwent major elective surgery between May 2020 and June 2023; 150 had complete information at 3-months (T3). Decline in performance status, either functional or cognitive, was defined as a ≥ 10-point worsening in the Barthel Index (BI) or death, or a ≥ 3-point decline in Mini-Mental State Examination (MMSE), all measured 3 months after surgery. Results: Mean (SD) age was 77 (5) years, with a mean (SD) Charlson Comorbidity Index (CCI) of 7 (2). Most surgeries (133, 79%) were performed for oncologic indications. Baseline median [IQR] BI was 100 [100-100], and MMSE was 27 [25-28]. At T3, 44 (29%) patients showed a ≥ 10-point BI decline ( Conclusion: Major elective surgery may compromise functional status in nearly one-third of older patients, especially those with high comorbidity and post-discharge sequelae. Cognitive decline was less prevalent, and the need for domiciliary or institutional care was relatively low.
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Registered trials
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