Evidence map›Paper›PMID 41189884›Full record

ArticleFrontiers in medicine2025

Olaf Tyc, Nico Kraus, Toska Wiedemann, Hans-Peter Erasmus, Cristina Ortiz, Jessica Vasseur, Kai Hourfar, Christian Seidl, Marcus Maximilian Mücke, Holger Storf and 7 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Olaf TycMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Nico KrausMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Toska WiedemannMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Hans-Peter ErasmusMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Cristina OrtizMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Jessica VasseurInstitute of Medical Informatics, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Kai HourfarInstitute for Transfusion Medicine and Immunohematology, German Red Cross Blood Donation Service Baden-Wuerttemberg-Hessen, Frankfurt am Main, Germany.
Christian SeidlInstitute for Transfusion Medicine and Immunohematology, German Red Cross Blood Donation Service Baden-Wuerttemberg-Hessen, Frankfurt am Main, Germany.
Marcus Maximilian MückeMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Holger StorfInstitute of Medical Informatics, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Iulia DahmerInstitute of Biostatistics and Mathematical Modeling, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Eva HerrmannInstitute of Biostatistics and Mathematical Modeling, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Stefan ZeuzemMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Volkhard A J KempfInstitute for Medical Microbiology and Infection Control, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Jonel TrebickaMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Christoph WelschMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Angela BriegerMedical Clinic 1, Biomedical Research Laboratory, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cirrhosis is a major global health burden, with acute-on-chronic liver failure (ACLF) being a severe complication associated with high mortality. Systemic inflammation (SI) plays a crucial role in ACLF development, yet indicators for predicting disease progression remain limited.

Indexed as

acute-on-chronic-liver-failurebacterial translocationchronic liver diseasesEnterococcus faeciumgut barriergut dysbiosisinflammationmicrobiome

Identifiers

PMID41189884
PMCPMC12580341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.