Evidence map›Paper›PMID 41189854›Full record

ArticleCureus2025

A Case of Rapidly Progressive Subglottic Hemangioma in an Infant: Early Propranolol Therapy Prevented Tracheostomy.

Genki Iwai, Takeshi Takahashi, Hironori Baba, Ko Matsui, Arata Horii

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Genki IwaiOtolaryngology - Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, JPN.
Takeshi TakahashiOtolaryngology - Head and Neck Surgery, Niigata University, Niigata, JPN.
Hironori BabaOtolaryngology - Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, JPN.
Ko MatsuiPediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, JPN.
Arata HoriiOtolaryngology - Head and Neck Surgery, Niigata University Hospital, Niigata, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subglottic hemangioma is a rare but potentially life-threatening cause of neonatal airway obstruction. We report the case of a preterm infant who developed rapidly progressive biphasic stridor at 36 days of life. Flexible laryngoscopy revealed a subglottic mass, and contrast-enhanced computed tomography demonstrated a well-circumscribed, enhancing lesion causing >70% airway narrowing. Following careful airway planning, the patient was intubated safely and treated with oral propranolol, resulting in marked regression within 10 days and successful extubation without tracheostomy. The infant remained symptom-free, with no recurrence at 24 months. This case highlights the importance of early recognition of biphasic stridor, prompt laryngoscopic evaluation, and timely propranolol initiation, which may avert invasive surgical interventions.

Indexed as

airway obstructionhemangiomainfant newbornpropranololsubglottis

Identifiers

PMID41189854
PMCPMC12580773

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.