Evidence map›Paper›PMID 41189820›Full record

ArticleCureus2025

Accuracy of the Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) and Alvarado Score for Acute Appendicitis: A Comparative Study.

Zakia Sultana, Gohar Ali, Haq Nawaz, Jawad Ali, Anees Ahmed, Aiman Ali, Muhammad Tahir, Yousaf Jan

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Zakia SultanaDepartment of General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Gohar AliDepartment of General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Haq NawazDepartment of General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Jawad AliDepartment of Orthopedic Surgery, Khyber Teaching Hospital, Peshawar, PAK.
Anees AhmedDepartment of General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Aiman AliDepartment of General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Muhammad TahirGeneral Surgery, Naas General Hospital, Naas east, IRL.
Yousaf JanDepartment of General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute appendicitis is the most frequent surgical emergency worldwide, but due to atypical symptoms, its diagnosis is challenging. The Alverado score is widely used but is limited in Asian populations, prompting the development of the Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) score. This study aims to compare the accuracy of both systems. METHODOLOGY: A prospective study was conducted at Hayatabad Medical Complex, Peshawar, from August 2024 to September 2025, including 100 patients with suspected acute appendicitis. Both RIPASA and Alvarado scores were assessed and compared with intraoperative findings using the Gomez classification. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall diagnostic accuracy were calculated.

resultsThe mean patient age was 28.1 years; 54% were male. Common presenting features were anorexia (90%), tenderness (99%), rebound tenderness (94%), and pain migration (76%). The RIPASA score showed sensitivity of 91.9%, specificity of 64.3%, PPV of 94.1%, NPV of 56.3%, and accuracy 88%. The Alvarado score demonstrated sensitivity of 94.2%, specificity of 57.1%, PPV of 93.1%, NPV of 61.5%, and accuracy 89%. Receiver operating characteristic (ROC) analysis yielded an area under the curve (AUC) of 0.78 for RIPASA and 0.76 for Alvarado.

conclusionBoth the RIPASA and Alvarado scores demonstrated high accuracy, with Alvarado showing slightly higher sensitivity (94.2% vs. 91.9%) and RIPASA offering better specificity (64.3% vs. 57.1%). Overall, both scoring systems proved reliable tools for diagnosis, helping reduce negative appendectomy rates and improving clinical decision-making.

Indexed as

acute appendicitisalverado scorediagnosis of acute appendicitisdiagnostic accuracy analysisripasa score

Identifiers

PMID41189820
PMCPMC12582032

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