Evidence map›Paper›PMID 41189766›Full record

ReviewJournal of experimental orthopaedics2025

Surgical and conservative management of medial plica syndrome: A systematic review and meta-analysis of functional outcomes.

Piero Franco, Philipp Baumert, Fabrizio Di Maria, Angad Jolly, Fabrizio Matassi, Elisabeth Abermann, Riccardo D'Ambrosi, Christian Fink

Abstract readReview
In one paragraph

Review in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Piero FrancoDepartment of Clinical Orthopaedics University of Florence Florence Italy.ORCID https://orcid.org/0000-0002-6650-6050
Philipp BaumertResearch Unit for Orthopaedic Sports Medicine and Injury Prevention Institute for Sports Medicine, Alpine Medicine and Health Tourism, FIFA Medical Centre of Excellence UMIT TIROL - Private University For Health Sciences and Health Technology Hall in Tirol Austria.ORCID https://orcid.org/0000-0002-5463-1954
Fabrizio Di MariaDepartment of General Surgery and Medical Surgical Specialties Section of Orthopaedics and Traumatology, University Hospital Policlinico "Rodolico - San Marco", University of Catania Catania Italy.
Angad JollyDepartment of Orthopaedics FMHS SGT University Gurugram India.
Fabrizio MatassiDepartment of Clinical Orthopaedics University of Florence Florence Italy.
Elisabeth AbermannResearch Unit for Orthopaedic Sports Medicine and Injury Prevention Institute for Sports Medicine, Alpine Medicine and Health Tourism, FIFA Medical Centre of Excellence UMIT TIROL - Private University For Health Sciences and Health Technology Hall in Tirol Austria.
Riccardo D'AmbrosiIRCCS Istituto Ortopedico Galeazzi Milan Italy.ORCID https://orcid.org/0000-0002-1216-792X
Christian FinkResearch Unit for Orthopaedic Sports Medicine and Injury Prevention Institute for Sports Medicine, Alpine Medicine and Health Tourism, FIFA Medical Centre of Excellence UMIT TIROL - Private University For Health Sciences and Health Technology Hall in Tirol Austria.ORCID https://orcid.org/0000-0002-8446-2434

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Knee plica syndrome is a common condition that often presents diagnostic challenges due to its symptom overlap with other knee pathologies. Surgical resection has traditionally been the common treatment; however, recent studies have questioned its necessity, proposing conservative interventions as effective alternatives. The aim of the current systematic review and meta-analysis is to analyse and compare efficacy of surgical and conservative treatment. Methods: A comprehensive review and meta-analysis was conducted on six clinical trials published between 2008 and 2023, focusing on surgical and conservative treatments for isolated knee plica syndrome. Rigorous inclusion criteria filtered studies that directly compared surgical and conservative methods. The risk of bias was assessed using the ROBINS-I tool for nonrandomized studies and RoB-2 for randomised trials. The studies were evaluated using patient-reported outcome measures and the pain score. The meta-analysis was carried out using the Lysholm Knee Score. Furthermore, complications and revisions surgery were recorded when reported. Results: The total number of patients investigated was 527 of which 284 were female (57%) and 209 males (43%). Patients were divided in two group according to the received treatment: both surgical and conservative treatments demonstrated improvements in knee function ( Conclusion: This study provides valuable insights into the treatment of knee plica syndrome, advocating for a conservative-first approach. Establishing standardised protocols could enhance diagnostic precision and patient outcomes, ultimately optimising management strategies for this complex knee pathology. Level of Evidence: Level IV.

Indexed as

anterior knee painchronic painkneeplica syndrome

Identifiers

PMID41189766
PMCPMC12581807

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.