ArticleJournal of biomedical optics2025
Multifocal optical coherence tomography of the mouse eye to image the vitreoretinal vasculature in full depth.
Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Depth-of-focus enhancement in optical coherence tomography via a cascaded image registration and fusion network for multi-focus imaging.Journal of biomedical optics · 2026Article
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4 authors.
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Abstract
Significance: Aim: Our aim is to develop a multifocal OCT imaging approach using a tunable lens and a registration method that allows the generation of a composite image of the vitreoretinal vasculature while preserving high and uniform lateral spatial resolution, signal intensity, and image contrast in full depth. Approach: A calibration target was developed to characterize the multifocal optical system and quantify the signal intensity, contrast, and resolution. These optical specifications were used to image mice at postnatal day 14. Intra- and inter-volume registration methods were necessary to correct for motion and generate a composite image from single-focus images using weighted averaging. Results: In the calibration target, signal intensity and contrast were 20 dB higher in the composite compared with single-focus images. Lateral resolution remained uniform (4 to Conclusions: This technique is promising in studying the mouse vitreoretinal vasculature during eye development and disease.
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