Evidence map›Paper›PMID 41189667›Full record

ReviewTherapeutic advances in gastroenterology2025

Linked color imaging for the detection and treatment of serrated colon neoplasia: current status and future perspective.

Menghui Wang, Yujing Xia, Jie Lu

Abstract readReview
In one paragraph

Review in Therapeutic advances in gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Menghui WangDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yujing XiaDepartment of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Yanchang Road, Shanghai 200072, China.
Jie LuDepartment of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 85 Wujin Road, Hongkou District, Shanghai 200080, China.ORCID https://orcid.org/0000-0002-1814-2125

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) remains the second leading cause of global cancer-related mortality, with serrated colon neoplasia (SCN) accounting for 20%-30% of cases. SCN exhibits distinct clinicopathological and molecular features, whose superficial and pale appearance poses challenges for endoscopic detection. Linked Color Imaging (LCI) significantly improves lesion detection by enhancing color contrast through narrowband preprocessing and post-processing augmentation, demonstrating superior performance in large-lumen examinations. This review synthesizes current knowledge on the clinicopathological and molecular profiles of SCN, elaborates on the technical advantages of LCI over conventional imaging modalities, and highlights its diagnostic utility in SCN screening. Furthermore, we explore the innovative integration of LCI with artificial intelligence for real-time lesion recognition and with biomedical nanomaterials for targeted therapy, proposing a promising "detection-treatment" paradigm that may transform early CRC management.

Indexed as

artificial intelligencebiomedical nanomaterialslinked color imagingscreeningserrated colon neoplasia

Identifiers

PMID41189667
PMCPMC12580531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.