ArticleFrontiers in neurology2025
Deep medullary veins disruption in cerebral small vessel disease: links to AI-quantified lesions and cognitive decline.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Deep medullary vein abnormalities associated with cognitive function and Alzheimer's disease plasma biomarkers in dementia-free older adults: A population-based study.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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10 authors.
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Abstract
Background: The relationship between cerebral small vessel diseases (CSVD) and deep medullary veins (DMV) has been the subject of only a limited number of studies to date, with the majority of research focusing on the correlation between DMV and cognitive function in patients with CSVD. The present study aims to quantitatively evaluate the relationship between DMV and CSVD imaging markers, utilizing an artificial intelligence neuroimaging system to achieve this objective. Furthermore, an investigation was conducted into the correlation between DMV disruption and cognitive impairment. Methods: This cross-sectional study enrolled patients with CSVD imaging markers who were admitted to the Department of Neurology at our hospital. The quantitative assessment of CSVD imaging markers, encompassing white matter hyperintensities (WMH), lacunar infarction (LI), and cerebral microbleeds (CMB), was conducted employing the AccuBrain Results: The study's sample population comprised 171 patients. Multivariate ordinal logistic regressions indicated that DMV score was significantly associated with WMH volume, LI count, and CMB count ( Conclusion: DMV score is associated with the severity of WMH, CMB, and LI, as well as cognitive performance decline, implicating that cerebral venule damage may play a role in the development of CSVD and related cognitive impairment.
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