Evidence map›Paper›PMID 41189637›Full record

ArticleBiochemistry and biophysics reports2025

Predicting metabolic preferences through transcriptomics: a data-driven approach to align metabolic signatures with gene expression profiles.

Lente J S Lerink, Marleen J de Winter, Jaap A Bakker, Ian P J Alwayn, Rutger J Ploeg, John F Mulvey, Jan H N Lindeman

Abstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lente J S LerinkDepartment of Surgery & Transplant Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.
Marleen J de WinterDepartment of Surgery & Transplant Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.
Jaap A BakkerLaboratory Genetic Metabolic Diseases, Amsterdam University Medical Centre, Location AMC, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands.
Ian P J AlwaynDepartment of Surgery & Transplant Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.
Rutger J PloegDepartment of Surgery & Transplant Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.
John F MulveyNuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom.
Jan H N LindemanDepartment of Surgery & Transplant Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex organisms such as mammals have a sophisticated metabolic network to meet energy demand under varying conditions. This network, which includes the exchange of metabolites between organs, is absent in

Indexed as

Arteriovenous measurementsMetabolic fluxMetabolismSubstrate preferenceTranscriptome profilesTranscriptomics

Identifiers

PMID41189637
PMCPMC12580596

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.