Evidence map›Paper›PMID 41189554›Full record

ArticleClinical interventions in aging2025

Factors Associated with Frailty Transitions Using the Kihon Checklist: A 6-Year Longitudinal Study Among Japanese Residents.

Norio Imai, Daisuke Homma, Yoji Horigome, Takuya Yoda, Reiko Murakami, Toshihide Fujii, Masayuki Ohashi, Hiroyuki Kawashima

Abstract read
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Article in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Norio ImaiDivision of Comprehensive Musculoskeletal Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.ORCID 0000-0003-2289-7499
Daisuke HommaDivision of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Yoji HorigomeDivision of Comprehensive Musculoskeletal Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Takuya YodaDivision of Comprehensive Musculoskeletal Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Reiko MurakamiDivision of Comprehensive Musculoskeletal Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Toshihide FujiiDepartment of Orthopedic Surgery, Agano City Hospital, Agano, Japan.
Masayuki OhashiDivision of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Hiroyuki KawashimaDivision of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Kihon Checklist (KCL) is widely used in Japan to assess robustness, pre-frailty, and frailty. However, the specific KCL items that predict the maintenance of robustness or transitions between frailty states remain unclear. Identifying these predictors could guide preventive strategies in older adults. This study examined item-level predictors of frailty transitions in a community-dwelling population over 6 years. Methods: This longitudinal non-interventional study followed residents aged 70 years in 2016 and 76 years in 2022 in Agano City, Japan. Health status was evaluated using the 25-item KCL, and frailty states (robust, pre-frail, frail) were classified by total scores. Changes in responses to each item (yes-to-yes, yes-to-no, no-to-yes, no-to-no) were analyzed. Multivariate logistic regression identified independent predictors of maintaining robustness, transitioning to pre-frailty or frailty, and improving from frailty. Results: Among the 358 participants that completed both surveys, robustness decreased from 60.9% to 48.6%. Maintaining robustness was independently associated with visiting friends and absence of fear of falling. Transition to pre-frailty was linked with loss of stair-climbing ability, difficulty eating tough foods, and impaired date orientation. Transition to frailty was associated with persistently low body mass index, reduced outings, memory loss recognized by others, and difficulty performing routine tasks. Improvement from frailty was predicted by initiating weekly outings. Conclusion: Key protective factors included social engagement, absence of fear of falling, oral function, cognitive health, and maintaining body weight. Regular outings prevented frailty and facilitated recovery, highlighting practical community-level intervention targets. Future research should test whether programs targeting these predictors reduce frailty incidence and improve recovery.

Indexed as

ChecklistFrail ElderlyFrailtyGeriatric AssessmentAccidental FallsAgedAged, 80 and overEast Asian PeopleFemaleHealth StatusHumansIndependent LivingJapanLongitudinal StudiesMalefrailtyimportant factorsKihon checklistlongitudinal study

Identifiers

PMID41189554
PMCPMC12581826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.