Evidence map›Paper›PMID 41189480›Full record

ArticleRestorative dentistry & endodontics2025

The influence of bioactive glass (BGS-7) on enamel remineralization: an in vitro study.

Chaeyoung Lee, Eunseon Jeong, Kun-Hwa Sung, Su-Jung Park, Yoorina Choi

Abstract read
In one paragraph

Article in Restorative dentistry & endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bacterial ghosts (BGs): A promising approach as candidate vaccine.World journal of microbiology & biotechnology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chaeyoung LeeDepartment of Conservative Dentistry, School of Dentistry, Wonkwang University, Iksan, Korea.
Eunseon JeongDepartment of Conservative Dentistry, School of Dentistry, Wonkwang University, Iksan, Korea.
Kun-Hwa SungDepartment of Conservative Dentistry, School of Dentistry, Wonkwang University, Iksan, Korea.
Su-Jung ParkDepartment of Conservative Dentistry, School of Dentistry, Wonkwang University, Iksan, Korea.
Yoorina ChoiDepartment of Conservative Dentistry, School of Dentistry, Wonkwang University, Iksan, Korea.

Funding

National Research Foundation of Korea NRF-2022R1G1A1010061
6 · The paper itself

Abstract

Objectives: The aim of this study was to compare the remineralizing capacity of bioactive glass (BGS-7, CGBIO) with other agents. Methods: Twenty caries-free third molars were sectioned and demineralized. Specimens were divided into four groups: (1) control, (2) Clinpro XT varnish (Solventum), (3) 1.23% acidulated phosphate fluoride gel, and (4) a new type of CaO-SiO2-P2O5-B2O3 system of bioactive glass ceramics (BGS-7). Agents were applied and stored in simulated body fluid at 37℃ for 2 weeks. Microhardness was measured using the Vickers hardness testing method. Five specimens per group were analyzed using quantitative light-induced fluorescence (QLF) to assess mineral loss. Field-emission scanning electron microscopy (FE-SEM) and energy-dispersive X-ray spectroscopy (EDS) were used to examine the surface morphology and elemental composition. Data were analyzed using paired t-test and one-way analysis of variance (p < 0.05). Results: BGS-7 showed the highest microhardness values and the greatest recovery in QLF analysis (p < 0.05). FE-SEM revealed granular precipitates on demineralized enamel in the BGS-7 group. EDS confirmed the presence of newly formed silicon and fluoride layers. Conclusions: BGS-7 demonstrated superior remineralization capacity compared to other agents, suggesting its potential as an effective remineralizing material.

Indexed as

Bioactive glassDental enamelQuantitative light-induced fluorescenceTooth demineralizationTooth remineralization

Identifiers

PMID41189480
PMCPMC12707567

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.