Evidence map›Paper›PMID 41189477›Full record

ArticleThe FEBS journal2026

Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract.

Natalie Hager, Mélanie Elisabeth Gindt, Marcel Hövels, Jean-Lou Christian Michel Dorne, Uwe Deppenmeier

Abstract read
In one paragraph

Article in The FEBS journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Structure and function of periplasmic nitrate reductase.Biochemical Society transactions · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Natalie HagerInstitute of Microbiology and Biotechnology, University of Bonn, Germany.
Mélanie Elisabeth GindtInstitute of Microbiology and Biotechnology, University of Bonn, Germany.
Marcel HövelsInstitute of Microbiology and Biotechnology, University of Bonn, Germany.
Jean-Lou Christian Michel DorneMethodology and Scientific Support Unit, European Food Safety Authority (EFSA), Parma, Italy.
Uwe DeppenmeierInstitute of Microbiology and Biotechnology, University of Bonn, Germany.ORCID 0000-0002-7810-7663

Funding

European Food Safety Authority OC/EFSA/MESE/2022/04European Medicines Agency EMA/2020/46/L1.02
6 · The paper itself

Abstract

The human intestinal microbiota plays a vital role in health. One of the most protective benefits is the bacterial nitrogen metabolism of gut bacteria, which reduces nitrate (NO

Indexed as

BacteriaGastrointestinal MicrobiomeNitrite ReductasesColonEscherichia coliFecesHumansNitratesNitritesNitratesNitrite ReductasesNitritesgut microbiotahuman intestinal tractmicrobiomenitrogen metabolismnitrosamines

Identifiers

PMID41189477
PMCPMC12998184

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.