Evidence map›Paper›PMID 41189416›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2025

Functional connectivity of semantic and default mode networks during narrative comprehension.

Melissa Thye, Junhua Ding, Paul Hoffman, Daniel Mirman

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melissa ThyeDepartment of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, United Kingdom.ORCID 0000-0002-6383-6361
Junhua DingState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Beijing 100101, China.
Paul HoffmanDepartment of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, United Kingdom.ORCID 0000-0002-3248-3225
Daniel MirmanDepartment of Psychology, University of Edinburgh, 7 George Square, Edinburgh EH8 9JZ, United Kingdom.ORCID 0000-0001-5472-0220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding narratives requires at least transient access to the semantic system, to decode incoming content, and prolonged access to the default mode network to maintain and manipulate the narrative model. Subregions within the integrative semantic hubs in bilateral anterior temporal lobe appear differentially sensitive to the need to rapidly decode external input (exogenous processing) versus reflecting on context stored in the narrative model (endogenous processing). The latter is most consistently reported in the middle temporal gyrus portion of the hub, suggesting that this region serves as a critical hinge point, dynamically interacting with the default mode network to facilitate endogenous processing. The present study investigated this by characterizing the functional connectivity profiles of anterior temporal lobe subregions during movie-viewing and examining content-evoked changes in these profiles. Compared to other anterior temporal lobe subregions, middle temporal gyrus was more functionally connected to the default mode network, and these connections were strengthened during moments with limited incoming information, providing viewers with a chance to reflect on the content. Rather than being functionally distinct networks, the semantic and default mode systems dynamically interact to facilitate reflection or endogenous semantic processing. Future work should further characterize how neural systems dynamically shift from integrated to segregated states in response to everyday processing demands.

Indexed as

ComprehensionDefault Mode NetworkNarrationSemanticsTemporal LobeAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysYoung Adultdefault mode networkfunctional MRImovie-viewingnarrative comprehensionsemantic cognition

Identifiers

PMID41189416
PMCPMC12586323

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.