Evidence map›Paper›PMID 41189296›Full record

ArticleEvolution & development2025

Is Telomere Length Optimized in Hatchling Sand Lizards?

Mats Olsson, Emily Miller, Nicky Rollings, Erik Wapstra, Richard Shine

Abstract read
In one paragraph

Article in Evolution & development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mats OlssonDepartment of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-4130-1323
Emily MillerOffice of the Deputy Vice-Chancellor (Research), The University of Sydney, Sydney, New South Wales, Australia.
Nicky RollingsSchool of Life and Environmental Sciences, The University of Sydney, Sydney, New South Wales, Australia.
Erik WapstraSchool of Natural Sciences, University of Tasmania, Hobart, Tasmania, Australia.ORCID 0000-0002-2050-8026
Richard ShineSchool of Natural Sciences, Macquarie University, Sydney, New South Wales, Australia.

Funding

This study was supported by the Swedish Science Council ('VR') and the Australian Research Council long term is acknowledged.
6 · The paper itself

Abstract

Telomeres (repeat-DNA-protein structures primarily located at the ends of chromosomes) protect coding DNA against attacks by reactive molecules and the cells' own DNA repair systems. If that capacity is costly, but enhances an individual's viability, we might expect to see natural selection acting on telomere length: that is, individuals with optimal telomere lengths should have higher lifetime reproductive success than conspecifics with shorter or longer telomeres. Some recent studies on humans broadly support that prediction, but no data are available for free-ranging ectothermic vertebrates that, unlike mammals, can facultatively adjust telomere length during an individual's lifetime. In our decade-long study of a natural population of sand lizards (Lacerta agilis), including measurement of 2736 telomeres across > 1700 hatchling lizards and their > 500 parents, but with a very high hatchling mortality reducing later-life sample sizes, we found that lifespan, lifetime reproductive success and offspring recruitment rate were highest for hatchlings with "average-length" telomeres. Hatchlings with shorter-than-average telomeres elongated their telomeres during juvenile life, attaining the population-average telomere length by the time of sexual maturity; but that compensatory telomere growth was associated with lower body condition.

Indexed as

LizardsTelomereTelomere HomeostasisAnimalsFemaleLongevityMaleReproductionadaptationhatchling telomere lengthLacertidaelife spanlifetime reproductive successoffspring recruitmentSquamatatelomere elongation

Identifiers

PMID41189296
PMCPMC12586907

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.