Evidence map›Paper›PMID 41189091›Full record

ArticleESC heart failure2025

Impact of standardized team-based care on cardiogenic shock outcomes over time.

Behnam N Tehrani, Carolyn M Rosner, Adetokunbo Fadahunsi, Kimberly Barker, Wayne B Batchelor, Vanessa Blumer, Lindsay Clevenger, Shashank Desai, Michelle Ferri, Evan Franke and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Behnam N TehraniInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.ORCID https://orcid.org/0000-0002-8037-7021
Carolyn M RosnerInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Adetokunbo FadahunsiGeorge Mason University, Fairfax, Virginia, USA.
Kimberly BarkerInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Wayne B BatchelorInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Vanessa BlumerInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Lindsay ClevengerInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Shashank DesaiInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Michelle FerriInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Evan FrankeInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Jamie KennedyInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Christopher KingInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Edward HowardInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Iyad IssehInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Seiyon Ben LeeGeorge Mason University, Fairfax, Virginia, USA.
Aditya MehtaInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Mitchell PsotkaInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Ramesh SinghInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Shashank S SinhaInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Matthew W SherwoodInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Daniel TangInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Megan TerekInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Alexander G TruesdellInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Ilan VavilinInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
Christopher M O'ConnorInova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsLimited data exist regarding the impact of standardized care on cardiogenic shock (CS) outcomes over time. We aimed to investigate the influence of multidisciplinary management on CS outcomes following implementation of team-based protocols in 2017.

methodsA total of 1453 consecutive patients enrolled into a single-centre CS registry were divided into two time periods, 2017-2019 versus 2020-2022. Baseline characteristics, management and outcomes were compared. The primary endpoint was adjusted in-hospital mortality. Multivariable regression analysis was performed to evaluate change in outcomes over time.

resultsCompared with 2017-2019, more patients with CS were treated in 2020-2022 (930 vs. 523; P < 0.01). They more often presented to the Level 1 centre (52% vs. 45%; P = 0.01), with a higher proportion of heart failure-related CS (72% vs. 58%; P < 0.01) and Society for Cardiovascular Angiography and Interventions B and C CS (64% vs. 49%; P < 0.01). They were less likely to be managed with percutaneous ventricular assist devices (11% vs. 24%; P < 0.01) but more likely to receive veno-arterial extracorporeal membrane oxygenation (14% vs. 4%; P < 0.01) and heart transplantation (9% vs. 4%; P < 0.04). No differences were noted in in-hospital mortality [adjusted odds ratio (aOR) 0.81; 95% confidence interval (CI): 0.56-1.16; P = 0.25], major adverse cardiac and cerebrovascular events (aOR 1.21; 95% CI: 0.87-1.68; P = 0.26), stroke (aOR 1.11; 95% CI: 0.65-1.91; P = 0.71) or renal replacement therapy (aOR 0.95; 95% CI: 0.66-1.37; P = 0.77).

conclusionsStandardized care for CS was associated with consistent in-hospital mortality over time despite changes in presentation and management. Further research is needed to identify the optimal care model during the vulnerable post-discharge period.

Indexed as

Patient Care TeamRegistriesShock, CardiogenicAgedExtracorporeal Membrane OxygenationFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedRetrospective StudiesTime Factorsacute myocardial infarctioncardiogenic shockheart failuresystems of careteam‐based caretemporal trends

Identifiers

PMID41189091
PMCPMC12719795

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.