Evidence map›Paper›PMID 41188968›Full record

SynthesisReproductive health2025

Epidemiology of infertility and coping mechanisms in Ethiopia, 2025: a systematic review and meta-analysis.

Yilkal Dagnaw Melesse, Haile Amha, Asmamaw Getnet, Atsede Alle Ewunetie, Aysheshim Asnake Abneh, Getnet Gedif, Anteneh Lamesgen, Abebaw Abeje Muluneh

Abstract readSystematic ReviewMeta-AnalysisReview
In one paragraph

Synthesis in Reproductive health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yilkal Dagnaw MelesseDepartment of Midwifery, College of Medicine and Health Science, Debre Markos University, Debre Markos, Ethiopia. yilkal_dagnaw@dmu.edu.et.
Haile AmhaDepartment of Nursing, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Asmamaw GetnetDepartment of Nursing, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Atsede Alle EwunetieDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Aysheshim Asnake AbnehDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Getnet GedifDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Anteneh LamesgenDepartment of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Abebaw Abeje MulunehDepartment of Midwifery, College of Medicine and Health Science, Debre Markos University, Debre Markos, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfertility is much more than a quality-of-life concern. Its consequences stream into public health domains such as psychological distress, social stigma and marital disagreements. The estimation of infertility is one of the most crucial activities concerning informing policymakers. Therefore, this review was conducted to estimate the pooled prevalence of infertility and coping mechanisms in Ethiopia.

methodsThis systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guideline to adhere to standards in conducting and reporting of evidence synthesis. An internet-based search of noninterventional studies in Ethiopia was performed in CINAHL, EMBASE, PubMed/MEDLINE, Cochrane Library, Scopus, Web of Science, and Google Scholar. A total of 332 studies were screened, and only 11 studies satisfied the inclusion criteria. Studies were included if they described the prevalence and/or coping mechanisms of infertility. The Newcastle–Ottawa Scale and Joanna Briggs Institute critical appraisal checklist were used for quantitative and qualitative studies, respectively. The random-effects meta-analysis was done in Stata version 17, and forest plots, test of heterogeneity, and funnel plots were all generated.

resultsThe pooled prevalence of lifetime and/or specific period of infertility was 25.77% [95% CI: 20.10, 31.45], with a heterogeneity index (I2 = 99.48, P = 0.00). The subgroup prevalence of primary infertility was 22.76% [-0.95–46.47], with heterogeneity (I2 = 99.54, p = 00), and that of secondary was 12.67% [9.14–16.20], with I2 = 98.57, p = 0.00. Spiritual activity, medical treatment, cultural practice, seeking support from family, adoption, acceptance, having a godchild, estranged social life, helplessness, extramarital engagement, and marital separation were the identified coping mechanisms.

conclusionCompared with the global standard, the pooled prevalence of infertility in Ethiopia is relatively high. Most of the identified coping strategies of infertility were problem-focused mechanisms. The identified coping mechanisms were grouped in the following main themes: (i) seeking medical treatment, (ii) religious/spiritual practices, (iii) seeking social support, (iv) using cultural remedies, (v) acceptance, and (vi) avoidance/harmful behaviors. Policy makers, health authorities and professionals should improve the delivery of infertility prevention and treatment services and ensure coping support is culturally sensitive and integrated with the national health strategy.

Indexed as

Adaptation, PsychologicalInfertilityCoping SkillsEthiopiaFemaleHumansMalePrevalenceQuality of LifeCoping mechanismEthiopiaInfertilityPrevalenceSystematic review and meta-analysis

Identifiers

PMID41188968
PMCPMC12584460

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.