ArticleOrphanet journal of rare diseases2025
Global research landscape of autoimmune nodopathy: a 20-year bibliometric analysis (2005-2025).
Article in Orphanet journal of rare diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAutoimmune nodopathy (AN) is a recently recognized, rare immune-mediated neuropathy characterized by autoantibodies targeting nodal and paranodal proteins such as neurofascin-155 and contactin-1. Since its classification as a distinct entity in 2021 by European Academy of Neurology/Peripheral Nerve Society, scientific interest in AN has rapidly increased. This study aimed to conduct a comprehensive bibliometric analysis to identify research trends, influential publications, leading authors, institutions, and collaboration networks in the field of AN between 2005 and 2025.
methodsA literature search was performed in the Web of Science Core Collection using AN-related keywords. A total of 109 original English-language articles were included based on defined inclusion and exclusion criteria. VOSviewer and CiteSpace were used for network visualization and citation burst analysis. Descriptive statistics and trend projections were conducted using SPSS and Microsoft Excel.
resultsA marked increase in publications was observed after 2021, coinciding with the formal definition of AN. The most productive countries were France, Germany, Spain, and Japan. Querol Luis, Sommer Claudia, and Doppler Kathrin emerged as leading authors. Highly cited articles focused on the pathogenesis and antibody profiles of AN. Keywords such as "neurofascin," "IgG4," and "autoimmune nodopathy" dominated the thematic clusters.
conclusionThis is first bibliometric analysis to systematically examine the scientific landscape of AN. Despite growing research interest, there remains a significant gap in large-scale epidemiological studies and randomized controlled trials. Our findings provide a roadmap for future research, highlighting the importance of international collaboration and antibody-based stratification in the diagnosis and treatment of AN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.