ReviewBMC pediatrics2025
Rickettsia felis meningoencephalitis in a 10-year-old child: a case report and literature review.
Review in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Case Report: PediatricFrontiers in pediatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRickettsia felis is a zoonotic pathogen belonging to the Rickettsia genus. Infection of children with central nervous system Rickettsia felis is very rare, with only a few cases reported worldwide. CASE PRESENTATION: We conducted a retrospective analysis of the clinical data, laboratory tests, and imaging results for a pediatric patient diagnosed with Rickettsia felis meningoencephalitis. The patient, an adolescent, initially presented with fever and headache. The condition progressed rapidly within six hours of admission, manifesting as photophobia, lethargy, and nuchal rigidity. The cerebrospinal fluid (CSF) analysis revealed leukocytosis, while cranial magnetic resonance imaging displayed abnormal signals in both basal ganglia and frontal-parietal regions. Detection of Rickettsia felis was confirmed through targeted next-generation sequencing (tNGS) of the CSF. The patient underwent a comprehensive treatment regimen including doxycycline for infection control, alongside glucocorticosteroids and gammaglobulin to manage symptoms and reduce intracranial pressure. The child fully recovered. One month after admission to the hospital for treatment, the child recovered. A month later, the child's CSF was normal and the child recovered completely.
conclusionThis case underscores the importance of enhancing pediatricians' and infectious diseases and neurology experts' comprehension of Rickettsia felis meningoencephalitis through shared diagnostic and therapeutic insights.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.