Evidence map›Paper›PMID 41188723›Full record

ArticleBMC infectious diseases2025

Effects of the non-pharmaceutical interventions during the COVID-19 epidemic on hand, foot and mouth disease in Qingdao, China.

Xueling Xin, Dapeng Sun, Qing Liu, Cun Wang, Yan Liu, Yingkun Wang, Jing Jia

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xueling Xin *Qingdao Municipal Centre of Disease Control and Prevention, Qingdao Health Supervision Institute, No.175 Shandong Road, Qingdao City, Shandong Province, 266033, People's Republic of China.
Dapeng Sun *Shandong Provincial Center for Disease Control and Prevention, Jinan City, Shandong Province, People's Republic of China.
Qing LiuQingdao Women and Children's Health Care and Family Planning Service Center, Qingdao City, Shandong Province, People's Republic of China.
Cun WangQingdao Municipal Centre of Disease Control and Prevention, Qingdao Health Supervision Institute, No.175 Shandong Road, Qingdao City, Shandong Province, 266033, People's Republic of China.
Yan LiuQingdao Municipal Centre of Disease Control and Prevention, Qingdao Health Supervision Institute, No.175 Shandong Road, Qingdao City, Shandong Province, 266033, People's Republic of China.
Yingkun WangLaoshan District Center for Disease Control and Prevention, Qingdao City, Shandong Province, People's Republic of China.
Jing JiaQingdao Municipal Centre of Disease Control and Prevention, Qingdao Health Supervision Institute, No.175 Shandong Road, Qingdao City, Shandong Province, 266033, People's Republic of China. 18678904773@163.com.

Funding

Natural Science Foundation of Shandong Province ZR2020QH298
6 · The paper itself

Abstract

backgroundSince December 2019, COVID-19 has spread rapidly, leading to a global epidemic. The non-pharmaceutical interventions (NPIs) were implemented to control the transmission of COVID-19. Previous studies have shown that NPIs have co-benefits for the prevention of other infectious diseases. This study aimed to explore the impact of the NPIs on Hand, foot and mouth disease (HFMD) in Qingdao, China.

methodsMonthly reported HFMD cases and pathogens information during 2010-2023 in Qingdao were collected from the China Notifiable Disease Surveillance System. Descriptive epidemiology method was adopted to describe the epidemic trend of HFMD. The seasonal autoregressive integrated moving average (SARIMA) model was used to estimate the monthly HFMD cases during the COVID-19 period, and assessed the effect of NPIs on HFMD by different years and response levels. The effects across different subgroups stratified by gender and ages were also explored.

resultsDescriptive analysis showed that there were significant differences in the epidemic trend and main pathogens before and after the outbreak of COVID-19. A total of 10,170 cases were reported from 2020 to 2022, with an average decrease of 69.61% compared to the average cases from 2010 to 2019. We confirmed the optimal SARIMA (1,0,1)(1,1,0)

conclusionsThe implementations of NPIs during the COVID-19 pandemic effectively reduced the spread of HFMD. Hence, strengthening public health intervention remains a priority measure for preventing HFMD.

Indexed as

COVID-19Hand, Foot and Mouth DiseaseAdolescentAdultAgedChildChild, PreschoolChinaEpidemicsFemaleHumansInfantInfant, NewbornMaleMiddle AgedSARS-CoV-2COVID-19Foot and mouth diseaseHandNon-pharmaceutical interventionsSARIMA

Identifiers

PMID41188723
PMCPMC12584540

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.