Trial reportBMC geriatrics2025
Neither uni- nor multi-modal exercise interventions improved single- and dual-task gait performance in physically active healthy elderly - a pilot study.
Trial report in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Correction: Neither uni- nor multi-modal exercise interventions improved single- and dual-task gait performance in physically active healthy elderly - a pilot study.BMC geriatrics · 2026Article
- Effects of a Multimodal Exercise Intervention on Single- and Dual-Task Gait Performance in Older Patients with Open-Angle Glaucoma: A Pilot Study.Geriatrics (Basel, Switzerland) · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAging is an inevitable process leading, inter alia, to the loss of muscle mass as well as the decrease in physical and cognitive function. These age-related impairments translate into a reduced gait performance and an increased risk of falls, which can be tackled with resistance training, Unimodal intervention (UMI). However, Multimodal intervention (MMI), i.e. combined motor-cognitive and resistance training, might be a more promising approach to increase physical and cognitive function in old adults. Therefore, this pilot study aimed to investigate the effects of MMI, compared to UMI, on gait and cognitive performance in elderly participants. We hypothesized that MMI will increase gait and cognitive performance to a larger extent than UMI.
methodsIn this two-arm randomized controlled pilot study, 24 healthy active elderly participants completed the MMI (12 participants, 72.6 ± 5.4 years) and the UMI (12 participants, 70.4 ± 5.3 years). Both groups trained for 12 weeks, two times a week for 60 min, respectively. MMI consisted of motor-cognitive training directly followed by resistance training, while UMI consisted of a stand-alone resistance training. Three weeks before and after the interventions, gait performance (e.g., stride length, velocity, minimum toe clearance) was assessed during single- and dual-task walking trials using inertial measurement units. During dual-task walking, participants walked and concurrently performed different cognitive tasks in a random order: (i) reaction time task, (ii) N-back-task, and (iii) letter fluency task with two difficulty levels, respectively. Data were analyzed with repeated measures analyses of covariance (Time×Intervention×Condition).
resultsAlthough the analyses of the progression of the external load used during resistance training showed a significant increase over the training period (e.g. leg press p < 0.001,[Formula: see text]=0.678), there was no improvement of gait or cognitive performance in active old adults after neither MMI nor UMI.
conclusionAgainst our hypothesis, the present pilot study indicated that neither a 12-week MMI nor UMI seems to have a sizable impact on gait parameters and cognitive performance in physically active healthy adults. Still, a significant increase in the external load used during resistance training was observed, implying neuromuscular adaptations, which, however, did not translate into a higher gait and/or cognitive performance. CLINICAL TRIAL NUMBER: German Clinical Trial Register ID: DRKS00022519/05.08.2020
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