Evidence map›Paper›PMID 41188666›Full record

ArticleJournal of general internal medicine2026

Implementing Advanced Comprehensive Diabetes Care Within the Veterans Affairs Learning Health System.

Matthew J Crowley, Sarah L Cutrona, Amy S Jeffreys, Summer Anderson, Brandolyn S White, Allison A Lewinski, Daniel J Amante, Sarah E McDannold, Andrea L Nevedal, Heather A King and 10 more

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Matthew J CrowleyDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA. matthew.crowley@va.gov.ORCID http://orcid.org/0000-0002-6205-4536
Sarah L CutronaCenter for Health Optimization and Implementation Research (CHOIR), Bedford, MA, USA.
Amy S JeffreysDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Summer AndersonDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Brandolyn S WhiteDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Allison A LewinskiDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Daniel J AmanteDivision of Health Informatics and Implementation Science, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Sarah E McDannoldCenter for Health Optimization and Implementation Research (CHOIR), Bedford, MA, USA.
Andrea L NevedalCenter for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Heather A KingDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Caitlin M ReardonCenter for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Marilla A Opra WiderquistCenter for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Maria E ArasimCenter for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Elisabeth SidoliVeterans Affairs Asheville Health Care System, Asheville, NC, USA.
Miriam A KirshnerDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Kathryn L DeLaughterCenter for Health Optimization and Implementation Research (CHOIR), Bedford, MA, USA.
Anna HungDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Matthew L MaciejewskiDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
Cynthia J CoffmanDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.
George L JacksonDurham Veterans Affairs Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham, NC, USA.

Funding

Foundation for the National Institutes of Health 1R01NR019594-01Health Services Research and Development 18-234Health Services Research and Development VA IIR 16-213Office of Rural Health NOMAD 3480Quality Enhancement Research Initiative QUE 20-012Quality Enhancement Research Initiative RRP 12-458
6 · The paper itself

Abstract

backgroundTelehealth can improve glycemic control for patients with type 2 diabetes (T2D), but programs must be designed in a manner that facilitates real-world uptake and effectiveness within learning health systems (LHS).

objectiveTo highlight how the Veterans Affairs (VA) LHS supports real-world practice change by examining Advanced Comprehensive Diabetes Care (ACDC), a telehealth program for persistently poor T2D control, in the context of the Learning Health System Consolidated Framework (LHS-CF) taxonomy.

designEvaluation of program implementation within an LHS.

participantsN = 1154 real-world ACDC participants

interventionsACDC is a 6-month program that leverages widely available VA telehealth infrastructure to deliver telemonitoring, self-management support, and medication management. MAIN MEASURES: In applying the LHS-CF, we accessed clinical hemoglobin A1c (HbA1c) data, examined ACDC encounter completion, and interviewed participants and staff. KEY

resultsACDC's development benefited from LHS-CF Enabling Conditions, including a workforce prepared to engage in structured learning and quality improvement; well-developed clinical data systems; strong VA investments in innovation; and a collaborative culture. Consequently, ACDC has contributed to multiple LHS-CF-aligned Bodies of Work, including building new evidence to improve T2D outcomes; translation of effective, telehealth-based T2D care into practice; authentic engagement of partners; ongoing analyses of data to support effective care; and development of new approaches to foster innovation and improvement. In practice, ACDC has reduced HbA1c from 9.7% at baseline to 8.0% at 6 months (-1.7%, 95% CI -1.7, -1.6, p < 0.0001), with retention of this benefit at 4 years; the program has been delivered with good fidelity and has been valued by participants and staff.

conclusionsThe conditions created by VA's LHS facilitate the development, testing, and implementation of programs like ACDC, which promote further LHS success. As a result of its intentional development within VA's LHS, ACDC is well-positioned to improve outcomes for Veterans with poorly controlled T2D nationwide.

Indexed as

Comprehensive Health CareDiabetes Mellitus, Type 2Learning Health SystemUnited States Department of Veterans AffairsDigital HealthGlycated HemoglobinHumansProgram EvaluationQuality ImprovementTelemedicineUnited StatesVeteransGlycated Hemoglobinclinical trial design and implementationprogram evaluationquality improvementrural healthVA healthcare system

Identifiers

PMID41188666
PMCPMC13631124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.