Evidence map›Paper›PMID 41188627›Full record

Observational studyEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

First episode of "probable benign paroxysmal positional vertigo, spontaneously resolved": a comparative and follow-up study.

Leticia Acle-Cervera, Leticia Carballo-Lahoz, Jonathan Esteban-Sánchez, María Guadalupe Álvarez-Morujo-de-Sande, María Alharilla Montilla-Ibáñez, Carmen Bécares-Martínez, Rocío González-Aguado, Isaura Rodríguez-Montesdeoca, Raquel Manrique-Huarte, Esther Domènech-Vadillo and 4 more

Abstract readMulticenter StudyObservational StudyComparative Study
PubMed Publisher
In one paragraph

Observational study in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leticia Acle-CerveraHospital Universitario Infanta Leonor, Madrid, Spain.
Leticia Carballo-LahozHospital Universitari Joan XXIII, Tarragona, Spain.
Jonathan Esteban-SánchezHospital Universitario de Getafe, Getafe, Spain.
María Guadalupe Álvarez-Morujo-de-SandeHospital de la Serranía de Ronda, Ronda, Spain.
María Alharilla Montilla-IbáñezHospital Universitario de Jaén, Jaén, Spain.
Carmen Bécares-MartínezHospital Universitario de Cabueñes, Gijón, Spain.
Rocío González-AguadoHospital Universitario Marqués de Valdecilla, Santander, Spain.
Isaura Rodríguez-MontesdeocaComplejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Spain.
Raquel Manrique-HuarteClínica Universidad de Navarra, Pamplona, Spain.
Esther Domènech-VadilloHospital Universitari Joan XXIII, Tarragona, Spain.
Gloria Guerra-JiménezComplejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Spain.
Esther Domènech-VadilloHospital Universitari Joan XXIII, Tarragona, Spain.
Gloria Guerra-JiménezComplejo Hospitalario Universitario Insular Materno-Infantil, Las Palmas de Gran Canaria, Spain.
Emilio Domínguez-DuránHospital QuironSalud Infanta Luisa, Sevilla, 41010, Spain. emiliodominguezorl@gmail.com.ORCID http://orcid.org/0000-0003-0088-5817

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBenign Paroxysmal Positional Vertigo (BPPV) is the most common cause of vertigo. A specific variant, "probable BPPV, spontaneously resolved" (pBPPVsr), is characterized by a history of positional vertigo without nystagmus or symptoms during clinical examination, leading clinicians to assume spontaneous resolution. This study was performed to compare the characteristics of patients with pBPPVsr and non-spontaneously resolved BPPV; to estimate the spontaneous resolution rate over time; to assess the sensitivity of the Dix-Hallpike test; and to monitor long-term recurrences and complications.

methodsProspective, multicenter observational study. Patients with a first episode of BPPV were recruited over one year and followed for an additional year. Inclusion criteria included a first-ever BPPV episode and no prior treatment. Patients were classified as pBPPVsr if no symptoms or nystagmus were elicited during positional tests. Group characteristics were compared, spontaneous resolution rates were estimated using Kaplan-Meier curves, and the Dix-Hallpike test sensitivity and complication rates (recurrence, headache, neck pain, falls, and PPPD) were assessed through scheduled follow-up calls.

resultsSpontaneous resolution occurred in 17-30% of cases, more frequently in younger patients without hypertension or diabetes, and typically within the first days of symptom onset. Dix-Hallpike test sensitivity was estimated at 97.7%. During follow-up, pBPPVsr patients more frequently triggered clinical suspicion of recurrence, and showed higher rates of new-onset headaches and neck pain.

conclusionpBPPVsr accounts for a substantial proportion of first-episode vertigo cases. Despite apparent resolution, patients remain at risk of recurrence and complications.

Indexed as

Benign Paroxysmal Positional VertigoAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRecurrenceRemission, SpontaneousBenign paroxysmal positional vertigoComplicationsPatient dischargeVertigo

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.