Evidence map›Paper›PMID 41188612›Full record

ArticlePrenatal diagnosis2025

Patient-Reported Outcome Measures in Fetal Medicine: A Pilot Feasibility Study.

N M T H Crombag, B Teeuwen, E M P Akkerman, B M E Adriaanse, A L Depla, A Franx, A J M Oerlemans, D Stemkens, L Henneman, M N Bekker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Prenatal diagnosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

N M T H CrombagDepartment of Obstetrics and Gynaecology, Wilhelmina Children's Hospital Utrecht, Utrecht University, Utrecht, the Netherlands.ORCID 0000-0002-6808-0874
B TeeuwenDepartment of Obstetrics and Gynaecology, Wilhelmina Children's Hospital Utrecht, Utrecht University, Utrecht, the Netherlands.ORCID 0009-0002-5795-0915
E M P AkkermanDepartment of Obstetrics and Gynaecology, Wilhelmina Children's Hospital Utrecht, Utrecht University, Utrecht, the Netherlands.
B M E AdriaanseDepartment of Obstetrics and Gynaecology, Wilhelmina Children's Hospital Utrecht, Utrecht University, Utrecht, the Netherlands.
A L DeplaDepartment of Obstetrics and Gynaecology, Wilhelmina Children's Hospital Utrecht, Utrecht University, Utrecht, the Netherlands.
A FranxDepartment of Obstetics and Gynaecology, Erasmus Medical Centre, Rotterdam, the Netherlands.
A J M OerlemansIQ Health Science Department, Radboud University Medical Center, Nijmegen, the Netherlands.ORCID 0000-0003-1791-1620
D StemkensVSOP-Patient Alliance for Rare and Genetic Diseases, Utrecht, the Netherlands.
L HennemanDepartment of Human Genetics, Amsterdam UMC, Location Vrije Universiteit, Amsterdam, the Netherlands.ORCID 0000-0003-3531-0597
M N BekkerDepartment of Obstetrics and Gynaecology, Wilhelmina Children's Hospital Utrecht, Utrecht University, Utrecht, the Netherlands.ORCID 0000-0002-7372-4291

Funding

Netherlands Organisation for Health Research and Development 05160472210001
6 · The paper itself

Abstract

objectiveA core set of generic Patient Reported Outcome Measures (PROMs) was recently developed to collect information from patients about their health status and quality of life. This study aims to: (1) identify relevant Patient Reported Outcome Measures (PROMs) from this core set for parents facing a fetal anomaly diagnosis and determine their optimal use and (2) assess the usability and feasibility of the adapted setting-specific PROMs in a Dutch Fetal Medicine Department.

methodA diverse expert panel of parents and healthcare professionals selected relevant PROMs along with their optimal timing and application. In a subsequent pilot feasibility study, parents completed the PROMs and discussed results with professionals. Responses were converted to T-scores using the PROMIS short forms. Usability and feasibility were assessed via questionnaires.

resultsTwenty-eight participants (19 parents, 9 professionals) agreed on two key PROMs: "ability to participate in social roles" and 'emotional distress (anxiety and depression)'. In the pilot study (n = 32; 21 parents, 11 professionals), PROMs were completed in 5.9 min on average, with participants opting to complete PROMs digitally from home. Parents found PROMs useful for enhancing communication with their partners and healthcare providers. The study identified the need for case managers, training on interpreting PROM results, a user-friendly Information Technology (IT) platform, and customized PROMs.

conclusionThis study shows potential benefits of PROMs in Fetal Medicine but encountered challenges regarding complexity, professional engagement, and time constraints in practice.

Indexed as

Patient Reported Outcome MeasuresPrenatal DiagnosisAdultFeasibility StudiesFemaleHumansMaleNetherlandsParentsPilot ProjectsPregnancyQuality of LifeSurveys and Questionnaires

Identifiers

PMID41188612
PMCPMC12693008

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.