Evidence map›Paper›PMID 41188585›Full record

ArticleScientific reports2025

Effect of zinc oxide or selenium nanoparticles on body weight, growth related genes and physiology in Baladi goats.

Ibrahim M Farag, Wael M Aboulthana, Shimaa M Ali, Mohamed I El Sabry, Mahmoud Y Mohamed, Mahmoud E Abd El-Aziz, Mariam G Eshak, Wagdy K B Khalil, Hayam Mansour

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ibrahim M FaragDepartment of Cell Biology, Biotechnology Research Institute, National Research Centre, 33 El Bohouth St, P.O. 12622, Dokki, Giza, Egypt. faragim@hotmail.com.
Wael M AboulthanaBiochemistry Department, Biotechnology Research Institute, National Research Centre, 33 El Bohouth St, P.O. 12622, Dokki, Giza, Egypt.
Shimaa M AliAnimal Production Research Institute (APRI), Agricultural Research Center (ARC), Dokki, 12611, Giza, Egypt.
Mohamed I El SabryAnimal Production Department, Faculty of Agriculture, Cairo University, 6 El-Gamma St, Giza, 12613, Giza, Egypt.
Mahmoud Y MohamedAnimal Production Research Institute (APRI), Agricultural Research Center (ARC), Dokki, 12611, Giza, Egypt.
Mahmoud E Abd El-AzizPolymers and Pigments Department, National Research Centre, 33 El Bohouth St, P.O. 12622, Dokki, Giza, Egypt.
Mariam G EshakDepartment of Cell Biology, Biotechnology Research Institute, National Research Centre, 33 El Bohouth St, P.O. 12622, Dokki, Giza, Egypt.
Wagdy K B KhalilDepartment of Cell Biology, Biotechnology Research Institute, National Research Centre, 33 El Bohouth St, P.O. 12622, Dokki, Giza, Egypt.
Hayam MansourDepartment of Cell Biology, Biotechnology Research Institute, National Research Centre, 33 El Bohouth St, P.O. 12622, Dokki, Giza, Egypt. hayammansour@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhancing meat production is essential to meet the rising global demand for animal protein, improve food security, and support sustainable agriculture. This study evaluated the effects of zinc oxide (ZnO) and selenium (Se), each administered individually in conventional or nanoparticle (NP) forms on growth of Egyptian Baladi goats. Twenty-two pregnant Egyptian Baladi goats were divided into five groups, each receiving a different treatment via drinking water: 150 mg ZnO, 15 mg ZnO-NPs, 0.3 mg Se, or 0.03 mg Se-NPs. The control group received unsupplemented water. Treatments began 30 days before parturition and continued until weaning (90 days postpartum). Body weight, expression of GH, IGF-1, and leptin genes, along with physiological parameters, were evaluated. Goats receiving either ZnO-NPs or Se-NPs had significantly higher body weights at parturition and greater weight gain from birth to weaning than those in the conventional elements and control groups. Suckling kids from ZnO-NP or Se-NP-treated goats showed significantly higher birth and weaning weights, total body gain, and daily weight gain (P < 0.001), particularly in the ZnO-NP group. Gene expression analysis revealed upregulated GH and IGF-1 and leptin expression in ZnO-NP- and Se-NP-treated goats, with the highest levels observed in the Se-NPs group. Physiological analysis showed protein and esterase isoenzyme pattern changes in ZnO-treated goats, while Se caused no alterations. Neither ZnO nor Se affected catalase, peroxidase or α-amylase activity. These findings highlight the potential of ZnO-NPs and Se-NPs as effective and safe nutritional supplements for improving livestock productivity.

Indexed as

Body WeightGoatsNanoparticlesSeleniumZinc OxideAnimalsFemaleInsulin-Like Growth Factor ILeptinPregnancyInsulin-Like Growth Factor ILeptinSeleniumZinc OxideBaladi goatsBody weightGene expressionPhysiological parametersSelenium nanoparticlesZinc oxide nanoparticles

Identifiers

PMID41188585
PMCPMC12586602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.