Evidence map›Paper›PMID 41188548›Full record

ArticleScientific reports2025

5-HT

Benedetta Fazari, Susanne Nikolaus, Owen Y Chao, Filipe Rodrigues Almeida, Laila Abdel-Hafiz, Markus Beu, Jan Henke, Christina Antke, Eduards Mamlins, Hubertus Hautzel and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Benedetta Fazari *Institute of Anatomy II, Medical Faculty, Heinrich-Heine University, Universitätsstr. 1, 40225, Düsseldorf, Germany.
Susanne Nikolaus *Clinic of Nuclear Medicine, Medical Faculty, Heinrich-Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany. susanne.nikolaus@uni-duesseldorf.de.
Owen Y ChaoGraduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, Taiwan.
Filipe Rodrigues AlmeidaInstitute of Anatomy II, Medical Faculty, Heinrich-Heine University, Universitätsstr. 1, 40225, Düsseldorf, Germany.
Laila Abdel-HafizInstitute of Anatomy II, Medical Faculty, Heinrich-Heine University, Universitätsstr. 1, 40225, Düsseldorf, Germany.
Markus BeuClinic of Nuclear Medicine, Medical Faculty, Heinrich-Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Jan HenkeClinic of Nuclear Medicine, Medical Faculty, Heinrich-Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Christina AntkeClinic of Nuclear Medicine, Medical Faculty, Heinrich-Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Eduards MamlinsClinic of Nuclear Medicine, Medical Faculty, Heinrich-Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Hubertus HautzelClinic for Nuclear Medicine, University Hospital Essen, University Duisburg Essen, Hufelandstraße 55, 45122, Essen, Germany.
Hans-Wilhelm MüllerClinic of Nuclear Medicine, Medical Faculty, Heinrich-Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.
Joseph P HustonCenter for Behavioural Neuroscience, Institute of Experimental Psychology, Heinrich-Heine University, Universitätsstr. 1, 40225, Düsseldorf, Germany.
Charlotte von GallInstitute of Anatomy II, Medical Faculty, Heinrich-Heine University, Universitätsstr. 1, 40225, Düsseldorf, Germany.
Frederik L GieselClinic of Nuclear Medicine, Medical Faculty, Heinrich-Heine University, Moorenstr. 5, 40225, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the effect of the 5-HT

Indexed as

Corpus StriatumDopamineGyrus CinguliMotor ActivityPyridinesReceptor, Serotonin, 5-HT1ASerotoninSerotonin 5-HT1 Receptor AntagonistsAnimalsBehavior, AnimalCatechol O-MethyltransferaseMaleMonoamine OxidasePiperazinesRatsRats, WistarCatechol O-MethyltransferaseDopamineMonoamine OxidaseN-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamidePiperazinesPyridinesReceptor, Serotonin, 5-HT1ASerotoninSerotonin 5-HT1 Receptor Antagonists5-HT1A receptorHigh performance liquid chromatographyMetabolizationWAY100,635

Identifiers

PMID41188548
PMCPMC12586442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.