ArticleNucleic acids research2026
Open Enzyme Database: a community-wide repository for sharing enzyme data.
Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Artificial intelligence and automation in enzyme engineering: evolution, advances, and future perspectives.Bioresources and bioprocessing · 2026Review
- Artificial Intelligence Powers Protein Functional Annotation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026Review
- The 2026 Nucleic Acids Research database issue and the online molecular biology database collection.Nucleic acids research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Enzymes are the molecular machines of life and play an indispensable role in numerous biotechnological and biomedical applications. Despite the availability of a few enzyme databases, their utility is often hindered by limitations such as infrequent updates, lack of standardization, and inadequate support for machine learning. In this study, we developed the Open Enzyme Database (OED), a community-wide repository and web-based infrastructure designed to facilitate the sharing and exploration of enzyme data. As a user-friendly platform, the first release of the OED provides extensively curated information on enzyme kinetic parameters, structural data, enzymatic reactions, assay conditions, and functional annotations. It also features cutting-edge artificial intelligence (AI) tools for enzyme property prediction, along with cheminformatics-powered algorithms for the identification of promising enzymes. This database should greatly accelerate research and applications in areas such as biocatalysis, systems biology, synthetic biology, and enzyme engineering, as well as AI. The resource is freely available at https://openenzymedb.platform.moleculemaker.org/.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.