Evidence map›Paper›PMID 41187998›Full record

Trial reportExperimental physiology2026

The impact of healthy motion seating on lower-limb blood flow and blood pressure response to simulated long-haul air travel.

Jane Lewis, Barry J Mcdonnell, Mark Butlin, Edward Johnston, Amira Tairi, Thomas Griffiths, Gisele Bentley, Peter Sykes, Keeron Stone

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jane LewisCentre for Cardiovascular Research, Innovation and Development (CURIAD), Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Barry J McdonnellCentre for Cardiovascular Research, Innovation and Development (CURIAD), Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.ORCID https://orcid.org/0000-0001-5912-1278
Mark ButlinFaculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia.
Edward JohnstonCentre for Cardiovascular Research, Innovation and Development (CURIAD), Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Amira TairiFaculty of Medicine, Université Laval, Quebec, Canada.
Thomas GriffithsCentre for Cardiovascular Research, Innovation and Development (CURIAD), Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.ORCID https://orcid.org/0009-0007-4876-4439
Gisele BentleyFaculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia.
Peter SykesCentre for Cardiovascular Research, Innovation and Development (CURIAD), Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Keeron StoneCentre for Cardiovascular Research, Innovation and Development (CURIAD), Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.ORCID https://orcid.org/0000-0001-6572-7874

Funding

Comfort Motion Global
6 · The paper itself

Abstract

Prolonged sitting inherent to long-haul air travel can acutely decrease lower-limb blood flow and increase brachial blood pressure. Healthy motion seating (HMS), which passively alters sitting interface pressure and posture, is a promising technology which may attenuate the deleterious effects of long-haul air travel. The aim of this study was to determine the impact of an innovative airplane passenger seat motion feature, aerospace HMS, on lower-limb blood flow and blood pressure in response to 6.5 h of simulated long-haul air travel. In a randomised cross-over design, 19 healthy adults completed a 6.5 h long-haul flight simulation in aerospace seating equipped with (HMS) and without (CON) healthy motion technology. Superficial femoral artery blood flow, brachial blood pressure, and perceptions of mood disturbance, pain and discomfort were measured before and after flight simulation. In linear mixed models there was a significant interaction (condition × time) effect for superficial femoral artery blood flow, with a decrease in lower-limb blood flow in CON (-22.4 mL/min; 95% CI: -2.41, -42.39; P = 0.032) but not HMS (3.7 mL/min; 95% CI: -16.3, 23.67; P = 0.720) across the 6.5 h flight simulation. There were no interaction, group nor time effects for blood pressure. Mood, pain and discomfort all worsened across the 6.5 h flight simulation (time, all P < 0.05), but there were no interaction nor group effects. The passive alterations in sitting interface pressure, posture and movement created by aerospace HMS can prevent prolonged sitting-induced reductions in local lower-limb blood flow typical of long-haul air travel.

Indexed as

Air TravelBlood PressureLower ExtremityPostureRegional Blood FlowAdultAircraftCross-Over StudiesFemaleFemoral ArteryHumansMaleSitting PositionYoung Adultaerospacemoodpainprolonged sittingpulse wave analysissedentary behaviour

Identifiers

PMID41187998
PMCPMC12949107

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.