Evidence map›Paper›PMID 41187352›Full record

ArticleJournal of breath research2025

Volatile organic compounds (VOCs) to monitor cell expansion and microbial contamination of mesenchymal stromal cells (MSCs): a preliminary study.

Manohar P Bhandari, Eva Borras, Dante E Rojas, Mitchell M McCartney, Hannah A Strobel, James B Hoying, Cristina E Davis

Abstract read
In one paragraph

Article in Journal of breath research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manohar P BhandariMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0003-2712-476X
Eva BorrasMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0002-4613-5328
Dante E RojasMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, United States of America.
Mitchell M McCartneyMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0001-7236-8400
Hannah A StrobelAdvanced Solutions Life Sciences, Manchester, NH, United States of America.ORCID 0000-0001-8738-4745
James B HoyingAdvanced Solutions Life Sciences, Manchester, NH, United States of America.ORCID 0000-0001-7959-227X
Cristina E DavisMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, United States of America.ORCID 0000-0002-9878-7758

Funding

Monitoring of disease-induced skin VOC patterns from handheld and wearable chemical sensorsU01TR004083 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CRISTINA ELIZABETH DAVIS, Nicholas J. KENYON · 2022 to 2026
$5.9M
Portable GC detector for breath-based COVID diagnosticsU18TR003795 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAVIS, CRISTINA ELIZABETH, KENYON, NICHOLAS J. · 2021 to 2022
$1.9M
NCATS NIH HHS U01 TR004083NCATS NIH HHS U18 TR003795
6 · The paper itself

Abstract

Several investigations have identified volatile organic compounds (VOCs) as potential biomarkers for the detection and identification of microbial contamination of metabolically active mammalian cell cultures. In this study, we showed that emitted VOCs discriminate between uncontaminated mesenchymal stromal cells (MSCs) and those contaminated with the bacterium

Indexed as

Mesenchymal Stem CellsVolatile Organic CompoundsCell ProliferationCells, CulturedGas Chromatography-Mass SpectrometryHumansPilot ProjectsVolatile Organic Compoundsbioreactorcell differentiationcell expansionmesenchymal stromal cells (MSC)microbial contamination detectionvolatile organic compounds (VOC)

Identifiers

PMID41187352
PMCPMC13038316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.