Evidence map›Paper›PMID 41187221›Full record

ArticleScience signaling2025

The chordoid glioma

Véronique Calleja, Jack C Henry, Mathias Cobbaut, Joanne Sewell, Karine Rizzoti, Francesca Houghton, Stefan Boeing, Nneka Anyanwu, Sunita Varsani-Brown, Thomas Snoeks and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science signaling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Véronique CallejaFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0002-6537-2660
Jack C HenryBarts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.ORCID 0000-0003-1521-5146
Mathias CobbautFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0003-0279-0336
Joanne SewellBarts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
Karine RizzotiFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0003-0711-5452
Francesca HoughtonFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0002-0797-3441
Stefan BoeingFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0003-0495-5659
Nneka AnyanwuFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0003-1044-1320
Sunita Varsani-BrownFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0002-7223-5998
Thomas SnoeksFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0003-3866-346X
Alejandro Suárez-BonnetRoyal Veterinary School, Hatfield AL9 7TA, UK.ORCID 0000-0003-0296-5896
Simon L PriestnallRoyal Veterinary School, Hatfield AL9 7TA, UK.ORCID 0000-0002-6027-1879
Neil Q McDonaldFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0003-0975-6325
Angus J M CameronBarts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.ORCID 0000-0003-3906-2789
Peter J ParkerFrancis Crick Institute, London NW1 1AT, UK.ORCID 0000-0001-5907-6980

Funding

Medical Research Council MR/X018997/1Wellcome Trust CC2068Wellcome Trust CC2140
6 · The paper itself

Abstract

The penetrant D463H mutation in

Indexed as

Brain NeoplasmsChondrosarcomaGain of Function MutationGliomaProtein Kinase C-alphaAllelesAnimalsCell Line, TumorGene Expression Regulation, NeoplasticGene Knock-In TechniquesHumansMiceMutationPrkca protein, mouseProtein Kinase C-alpha

Identifiers

PMID41187221
PMCPMC7618404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.