Evidence map›Paper›PMID 41187080›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

ENKD1 attenuates antibacterial immunity by facilitating TRIM21-mediated RUBCN degradation to suppress LC3-associated phagocytosis.

Caimeng Song, Lulu Sun, Jie Wang, Shujun Liu, Wenqing Xu, Cai Zhang, Jun Zhou, Tianliang Li, Yan Li

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. ENKD1 attenuates antibacterial immunity by facilitating TRIM21-mediated RUBCN degradation to suppress LC3-associated phagocytosis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caimeng Song *Center for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0009-0007-5275-9608
Lulu Sun *Center for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0001-5946-7770
Jie WangCenter for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0009-0007-5166-8608
Shujun LiuCenter for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0009-0001-6754-2440
Wenqing XuCenter for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.
Cai ZhangInstitute of Immunopharmacology and Immunotherapy, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China.ORCID 0000-0002-3849-6676
Jun ZhouCenter for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0003-3131-7804
Tianliang LiCenter for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0003-2673-0549
Yan LiCenter for Cell Structure and Function, College of Life Sciences, Shandong Normal University, Jinan 250358, China.ORCID 0000-0001-5609-1907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microtubule-associated protein 1A/1B-light chain 3 (LC3)-associated phagocytosis (LAP) plays a critical role in host defense against invading pathogens, including

Indexed as

Microtubule-Associated ProteinsPhagocytosisRibonucleoproteinsAnimalsFrancisellaHumansListeria monocytogenesListeriosisMacrophagesMiceMice, Inbred C57BLMice, KnockoutPhagosomesSalmonella typhimuriumSS-A AntigenMap1lc3b protein, mouseMicrotubule-Associated ProteinsRibonucleoproteinsSS-A Antigenantibacterial immunityENKD1LC3-associated phagocytosisRUBCNTRIM21

Identifiers

PMID41187080
PMCPMC12625919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.