Evidence map›Paper›PMID 41187001›Full record

ArticleClinical and translational science2025

Mass Balance and Metabolism of

Ramesh R Boinpally, Pushpa Chandrasekar, Joshua M Rowe

Abstract readClinical Trial, Phase I
In one paragraph

Article in Clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Mass Balance and Metabolism ofClinical and translational science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ramesh R BoinpallyClinical Pharmacology, AbbVie Inc., North Chicago, Illinois, USA.ORCID 0000-0001-8267-9210
Pushpa ChandrasekarLocal Delivery Translational Sciences, AbbVie Inc., Irvine, California, USA.ORCID 0009-0001-5068-9630
Joshua M RoweLocal Delivery Translational Sciences, AbbVie Inc., Irvine, California, USA.ORCID 0000-0001-6839-2926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atogepant, a calcitonin gene-related peptide (CGRP) receptor antagonist, is approved for the preventive treatment of migraine in adults. This open-label, phase 1 study examined radiolabeled atogepant (

Indexed as

Calcitonin Gene-Related Peptide Receptor AntagonistsQuinazolinesAdultCarbon RadioisotopesFecesHalf-LifeHealthy VolunteersHumansMaleMiddle AgedYoung AdultCalcitonin Gene-Related Peptide Receptor AntagonistsCarbon-14Carbon RadioisotopesQuinazolinesatogepanthumanmass balancemetabolismmetabolites

Identifiers

PMID41187001
PMCPMC12584159

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.