Evidence map›Paper›PMID 41186897›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026

Cost-effective CRT using dual-chamber generators in patients without atrial pacing need.

Pedro J Diaz Delgado, Aashish Katapadi, Douglas Darden, Dhanunjaya Lakkireddy, Rajesh Kabra, NagaVenkata K Pothineni

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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pedro J Diaz DelgadoKansas City Heart Rhythm Institute, 5100 W 110th Street, Suite 200, Overland Park, KS, 66211, USA.
Aashish KatapadiHCA Midwest Health, Overland Park, KS, USA.
Douglas DardenKansas City Heart Rhythm Institute, 5100 W 110th Street, Suite 200, Overland Park, KS, 66211, USA.
Dhanunjaya LakkireddyKansas City Heart Rhythm Institute, 5100 W 110th Street, Suite 200, Overland Park, KS, 66211, USA.
Rajesh KabraKansas City Heart Rhythm Institute, 5100 W 110th Street, Suite 200, Overland Park, KS, 66211, USA.
NagaVenkata K PothineniKansas City Heart Rhythm Institute, 5100 W 110th Street, Suite 200, Overland Park, KS, 66211, USA. NagaVenkata.Pothineni@hcahealthcare.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac resynchronization therapy (CRT) improves outcomes in patients with reduced left ventricular ejection fraction, but device cost limits access. In patients without atrial pacing needs, the atrial port of a dual-chamber pacemaker or ICD can be repurposed for conduction system pacing to deliver CRT. We retrospectively analyzed 18 patients who underwent left bundle branch area pacing using a dual-chamber generator. The left bundle branch lead was connected to the atrial port. Over 12 months, LVEF remained stable in patients with pacemakers, with modest QRS narrowing, and limited ICD data suggested LVEF improvement. No intra-procedural complications occurred, and one patient developed a self-resolving pericardial effusion. No inappropriate ICD therapies were observed. Cost analysis demonstrated savings of $3,922 per CRT-D and $2,963 per CRT-P device avoided. Delivering CRT via dual-chamber generators in patients without atrial pacing needs is feasible, safe, and cost-effective, potentially broadening access to CRT, particularly in resource-limited settings. Larger studies are needed to confirm these findings.

Indexed as

Cardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesHeart FailurePacemaker, ArtificialAgedCost-Benefit AnalysisFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAtrial fibrillationCardiac resynchronization therapyDual chamberEjection fractionLeft ventricle

Identifiers

PMID41186897

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.