Evidence map›Paper›PMID 41186882›Full record

ReviewArchives of pharmacal research2025

Structure, biological activity, and biosynthesis of natural chromanes and chromenes.

Ying Liu, Yang Xu, Na Zhang, Hua Li, Lixia Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of pharmacal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Vitamin BRSC advances · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying Liu *Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Yang Xu *Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Na ZhangKey Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Hua LiInstitute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. lihua@fjtcm.edu.cn.
Lixia ChenKey Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China. syzyclx@163.com.ORCID http://orcid.org/0000-0003-2196-1428

Funding

Foundation of Fujian University of Traditional Chinese Medicine X2023001-TalentProject of Frontier Technology Platform for Research Projects of Liaoning Provincial Department of Education in 2024 No. LJ232410163056"Select the best candidates to lead key research projects" of Fujian University of Traditional Chinese Medicine XJB2022008
6 · The paper itself

Abstract

Chromanes and chromenes with various biological activities are widespread in nature and have now been found in a variety of plants, fungi and marine organisms. To date, 79 previously undescribed chromanes and 161 previously undescribed chromenes have been isolated and identified. The chromanes were further classified into four skeleton types, and the chromenes were further classified into five skeleton types. In this review, natural chromanes and chromenes were classified according to their skeleton types, and their biological activities and biosynthetic pathways were also summarized. Pharmacological research has demonstrated that chromanes and chromenes possess a range of biological activities, including antimicrobial, anti-inflammatory, anticancer, antidiabetic, and insecticidal properties. This review provides an important reference for structural analysis, pharmacological activity studies, and biosynthetic pathways of chromanes and chromenes.

Indexed as

BenzopyransBiological ProductsChromansAnimalsAnti-Infective AgentsAntineoplastic AgentsHumansMolecular StructureStructure-Activity RelationshipAnti-Infective AgentsAntineoplastic AgentsBenzopyransBiological ProductsChromansBiological activityBiosynthesisChromaneChromeneSkeleton

Identifiers

PMID41186882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.