Evidence map›Paper›PMID 41186845›Full record

ArticleDiscover oncology2025

Collaboration networks and knowledge structure in cancer and cellular senescence research (2000-2025): a bibliometric perspective.

He Zhu, Shuangjia Pan, Yujia Zhou, Baozhu Yi, Yuqing Jing, Luyi Ruan, Lingxiao Huang, Xueqiong Zhu

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

He Zhu *Zhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Shuangjia Pan *Zhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Yujia ZhouZhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Baozhu YiZhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Yuqing JingZhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Luyi RuanZhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Lingxiao HuangZhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China.
Xueqiong ZhuZhejiang Provincial Clinical Research Center for Gynecological Diseases, Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang, China. zjwzzxq@163.com.

Funding

zhejiang Key Laboratory of Traditional chinese Medicine for Diagnosis and Treatment of Gynecological Cancers 2022-11
6 · The paper itself

Abstract

Cancer is a leading cause of death worldwide, posing substantial public health challenges. Cellular senescence, a stress-induced cell fate characterized by stable cell-cycle arrest and a hypersecretory state, plays dual roles in tissue repair and tumor suppression. Although the relationship between cancer and cellular senescence has been widely investigated, no comprehensive bibliometric analysis has been reported. This study aimed to map the global research landscape, identify hotspots, and reveal emerging trends in this field. Publications from 2000 to 2025 were retrieved from the Web of Science Core Collection, including only articles and reviews, and analyzed using VOSviewer and CiteSpace. A total of 5790 papers were identified, showing a steady increase in publications and citations over the past 25 years. The USA ranked first in publication output and institutional productivity, followed by China, while Judith Campisi was the most prolific and cited author. Hotspots included the senescence-associated secretory phenotype (SASP), immunotherapy, tumor microenvironment, secretory phenotype, and molecular hallmarks of senescence. These findings indicate that cancer and cellular senescence research is expanding rapidly, with secretory phenotypes and molecular hallmarks representing promising directions for future investigation.

Indexed as

BibliometricsCancerCellular senescenceCiteSpaceVisualized analysis

Identifiers

PMID41186845
PMCPMC12586263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.