Evidence map›Paper›PMID 41186827›Full record

ArticleBulletin of experimental biology and medicine2025

Alimentary Disorders of Cholesterol and Fat Metabolism in Male Wistar Rats: an In Vivo Study.

N A Biryulina, V K Mazo, N A Petrov, Yu S Sidorova, A A Kochetkova

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

N A BiryulinaFederal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia. biryulina_nadezhda@mail.ru.
V K MazoFederal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia.
N A PetrovFederal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia.
Yu S SidorovaFederal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia.
A A KochetkovaFederal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a comparative analysis of lipid and cholesterol metabolism disorders, as well as liver condition in male Wistar rats receiving high-fat diets with different cholesterol contents. Addition of 2% cholesterol to the diet resulted in a marked aggravation of fatty liver disease, characterized by extreme accumulation of fat and cholesterol. A diet supplemented with 0.5% cholesterol resulted in serum cholesterol accumulation and liver steatosis, but had no effect on weight gain or body composition. Introduction of 1% cholesterol to the diet induced similar abnormalities as 2% cholesterol, but without the extreme cholesterol and fat accumulation in the liver. This model can be used in the future to evaluate the effectiveness of the studied functional foods.

Indexed as

CholesterolFatty LiverLipid MetabolismAnimalsBody CompositionDiet, High-FatLiverMaleRatsRats, WistarCholesterolbiomodelingcholesterollipid metabolism disorders

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.