Evidence map›Paper›PMID 41186771›Full record

ArticleMarine biotechnology (New York, N.Y.)2025

Integrated Transcriptomic and Metabolomic Analyses Reveal the Adaptive Mechanisms of a Low-Salinity Selected Population of Pacific White Shrimp (Litopenaeus vannamei).

Yucong Ye, Junling Ma, Xinglin Du, Jiarong Huang, Yujie Zhou, Hang Liu, Yiming Li, Yunlong Zhao

Abstract read
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In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yucong YeSchool of Life Science, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Junling MaSchool of Life Science, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Xinglin DuSchool of Life Science, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Jiarong HuangSchool of Life Science, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Yujie ZhouSchool of Life Science, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Hang LiuSchool of Life Science, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Yiming LiEast China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai, 200090, China. liym@ecsf.ac.cn.
Yunlong ZhaoSchool of Life Science, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. ylzhao426@163.com.

Funding

Agriculture Research System of Shanghai, China 202205
6 · The paper itself

Abstract

Litopenaeus vannamei is one of the most widely farmed shrimp species worldwide, but it traditionally exhibits limited adaptability to low-salinity environments. Genetic improvement through intraspecific hybridization has been proven effective in enhancing environmental adaptability. This study aimed to elucidate the molecular mechanisms underlying the low-salinity adaptation of a hybrid shrimp strain selected through intraspecific hybridization. Shrimp were reared for 12 weeks under salinity conditions of 1 practical salinity unit (PSU) and 15 practical salinity units (PSU). By conducting a combined analysis of transcriptomics and metabolomics, we explored the low-salt adaptation mechanism of the hybrid shrimp. We found that they enhanced their adaptability through self-osmotic regulation and energy regulation. Transcriptome results revealed that genes associated with calcium-activated chloride channels, chloride transporters, and sodium-driven chloride/bicarbonate exchangers were up-regulated, suggesting enhanced ion transport capacity under low salinity. The metabolomics results indicated that key enzymes involved in glycolysis and gluconeogenesis, including phosphofructokinase and phosphoenolpyruvate carboxykinase, showed increased abundance, indicating elevated energy metabolism to support osmotic adjustment. Overall, the selected hybrid shrimp enhanced osmotic regulation by strengthening energy metabolism to improve their low-salt adaptability. These findings provide valuable insights for future genetic breeding and sustainable shrimp aquaculture in low-salinity regions.

Indexed as

Adaptation, PhysiologicalPenaeidaeSalt ToleranceTranscriptomeAnimalsEnergy MetabolismGene Expression ProfilingHybridization, GeneticMetabolomicsOsmoregulationSalinityHybrid strainIon transportLow-salinity toleranceMulti-omics analysisOsmoregulation

Identifiers

PMID41186771

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.