Evidence map›Paper›PMID 41186765›Full record

ArticleInternational ophthalmology2025

Age and gender differences in acquired nasolacrimal duct obstruction in a Saudi Arabian population.

Viana N Phan, Jiawei Zhao, Zakeya Al-Sadah, Ying Chen, Timothy J McCulley

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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Viana N PhanRuiz Department of Ophthalmology and Visual Science, McGovern Medical School at University of Texas Health Science Center, 6400 Fannin Street, Suite 1800, 77030, Houston, TX, US.ORCID http://orcid.org/0009-0007-1363-9814
Jiawei ZhaoWilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, US.ORCID http://orcid.org/0000-0002-1625-1176
Zakeya Al-SadahKing Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Ying ChenRuiz Department of Ophthalmology and Visual Science, McGovern Medical School at University of Texas Health Science Center, 6400 Fannin Street, Suite 1800, 77030, Houston, TX, US.
Timothy J McCulleyRuiz Department of Ophthalmology and Visual Science, McGovern Medical School at University of Texas Health Science Center, 6400 Fannin Street, Suite 1800, 77030, Houston, TX, US. timothy.j.mcculley@uth.tmc.edu.ORCID http://orcid.org/0000-0002-0757-9874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study assesses male to female NLDO incidence as a function of age in Saudi Arabia and compares the demographics to a western population.

methodsA retrospective review was conducted to identify patients who consecutively underwent dacryocystorhinostomy at King Khaled Eye Specialist Hospital between January 1, 2011 and April 31, 2012. Diagnosis of NLDO was confirmed by lacrimal irrigation as reported in clinical records, and patients with an identifiable cause of obstruction (i.e. trauma) were excluded. Demographic data (age and gender) were recorded.

resultsA total of 68 patients were identified (47 females, 21 males; mean age 44.5 ± 18.5). The overall male-to-female ratio was 1:2.2; however, acquired NLDO incidence was higher in men than women (ratio 1:0.75) in the 15-24 age group. The mean age in our study (44.5 years) was significantly younger than those in the Olmsted County series (59.5 years, p < 0.001). Compared to the Olmsted County series, there was a lower incidence ratio of female patients in the 15-24 age group within our population (male-to-female, 1:0.75 vs. 1:4.5).

conclusionsOur study found the mean age of patients with NLDO in a Saudi Arabian population is significantly younger than the mean age of a western population and a relatively higher incidence of NLDO in men than women under 25 years in the Saudi Arabian population. These demographic features may suggest different pathophysiologic mechanisms for the development of NLDO in the Saudi Arabian population. Whether these variations stem from genetic, environmental or other influences has yet to be established.

Indexed as

Lacrimal Duct ObstructionNasolacrimal DuctAdolescentAdultAgedAged, 80 and overAge DistributionAge FactorsDacryocystorhinostomyFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesSaudi ArabiaDacryocystorhinostomyEpidemiologyGender differencesNasolacrimal duct obstructionSaudi Arabia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.