Evidence map›Paper›PMID 41186743›Full record

ArticleEuropean journal of applied physiology2026

Physiological responses to cardiopulmonary and field exercise tests in primary ciliary dyskinesia compared with healthy peers.

Aslihan Cakmak-Onal, Elif Kocaaga, Hazal Sonbahar-Ulu, Ebru Calik, Naciye Vardar-Yagli, Melda Saglam, Birce Sunman, Nagehan Emiralioglu, Ugur Ozcelik, Deniz Inal-Ince

Registry-linked trialAbstract read
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In one paragraph

Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05712798 (Physiological Responses to Exercise Tests in Primary Ciliary Dyskinesia Compared With Healthy Children and Investigation of the Relationship Between Exercise Capacity and Quality of Life in Primary Ciliary Dyskinesia), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05712798 completednot on this map

Physiological Responses to Exercise Tests in Primary Ciliary Dyskinesia Compared With Healthy Children and Investigation of the Relationship Between Exercise Capacity and Quality of Life in Primary Ciliary Dyskinesia

TypeobservationalSponsorHacettepe UniversityRan2020 to 2023Enrolled46ConditionsPrimary Ciliary DyskinesiaArmsNo intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aslihan Cakmak-OnalFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye. aslihancakmak90@gmail.com.ORCID http://orcid.org/0000-0002-2474-8000
Elif KocaagaFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-5650-8992
Hazal Sonbahar-UluDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Akdeniz University, Antalya, Türkiye.ORCID http://orcid.org/0000-0002-7815-4072
Ebru CalikFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0001-5215-5125
Naciye Vardar-YagliFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0003-0218-140X
Melda SaglamFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0001-5323-1943
Birce SunmanFaculty of Medicine, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0001-9818-8782
Nagehan EmiraliogluFaculty of Medicine, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-1405-8401
Ugur OzcelikFaculty of Medicine, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0003-1587-5216
Deniz Inal-InceFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Türkiye.ORCID http://orcid.org/0000-0002-8151-0664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrimary ciliary dyskinesia (PCD) is a rare disorder characterized by defective motile cilia, impairing airway mucociliary clearance. Children with PCD (cwPCD) may exhibit distinctions in exercise responses compared to healthy peers (HP). We aimed to compare physiological responses to cardiopulmonary exercise testing (CPET), incremental shuttle walk test (ISWT), and 6-min walk test (6MWT) in cwPCD and HP and investigate the associations between clinical parameters.

methodsTwenty-three cwPCD and 23 HP were included. Pulmonary function and respiratory muscle strength were assessed. All participants performed CPET, ISWT, and 6MWT. Heart rate (HR), blood pressure (BP), oxygen saturation (SpO

resultsIn cwPCD, CPET and ISWT revealed similar HR, SpO

conclusionCPET and ISWT evoke comparable responses, while 6MWT results in lower physiological responses. However, 6MWT remains useful, given its association with peak CLINICALTRIALS: GOV IDENTIFIER: NCT05712798 (Registration Date: 26.01.2023).

Indexed as

Exercise TestKartagener SyndromeAdolescentChildFemaleHeart RateHumansMaleOxygen ConsumptionExerciseField testPrimary ciliary dyskinesiaQuality of life

Identifiers

PMID41186743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.